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基于文献计量学的心力衰竭中线粒体动力学可视化分析：趋势、热点和主题。

Visualization analysis of mitochondrial dynamics in heart failure based on bibliometrics: Trends, hotspots, and topics.

机构信息

Department of Cardiology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.

Department of Cardiology, Capital Medical University, Beijing, China.

出版信息

Medicine (Baltimore). 2024 Mar 15;103(11):e37598. doi: 10.1097/MD.0000000000037598.

DOI:10.1097/MD.0000000000037598
PMID:38489673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10939601/
Abstract

This study aimed to conduct a visual analysis of the relevant literature on mitochondrial dynamics in heart failure, explore the research progress, frontier topics, and development trends in this field, and provide references for the study concerning mitochondrial dynamics in the prevention and treatment of heart failure. The Web of Science was searched from inception to October 1, 2023 to identify relevant English literature on mitochondrial dynamics in heart failure. Bibliometric methods were utilized to statistically analyze the eligible literature, and CiteSpace 6.2.R5 software was employed to visualize data such as countries of publication, institutions, authors, and keywords. A total of 1755 Science Citation Index articles were included. The global publication volume showed an increasing trend year by year, with China and the United States having the most publications, and the United States displaying the highest centrality in publications. As revealed by keyword and citation analyses, the research hotspots and frontiers in this field mainly included the pathogenesis of heart failure, mitochondrial dynamics markers, mitochondrial quality control, and potential therapeutic targets for heart failure. Research on mitochondrial dynamics in heart failure is under vigorous development. It is a development trend in this research field to explore the differential gene expression and molecular mechanisms of targeted treatment in the mitochondrial dynamics in heart failure, which will contribute to the formulation of new strategies for the prevention and treatment of heart failure.

摘要

本研究旨在对视粒体动力学在心力衰竭相关文献进行可视化分析，探讨该领域的研究进展、前沿课题和发展趋势，为研究线粒体动力学在心力衰竭的防治中提供参考。检索 Web of Science 从建库至 2023 年 10 月 1 日，获取有关心力衰竭中线粒体动力学的英文文献。采用文献计量学方法对纳入文献进行统计分析，使用 CiteSpace 6.2.R5 软件对国家/地区、机构、作者和关键词等数据进行可视化处理。共纳入 1755 篇科学引文索引文献。全球发文量呈逐年递增趋势，发文量最多的国家/地区为中国和美国，美国在发文方面的中心度最高。通过关键词和引文分析发现，该领域的研究热点和前沿主要包括心力衰竭的发病机制、线粒体动力学标志物、线粒体质量控制以及心力衰竭的潜在治疗靶点。心力衰竭中线粒体动力学的研究正在蓬勃发展，探索心力衰竭中线粒体动力学的靶向治疗的差异基因表达和分子机制是该研究领域的发展趋势，将有助于制定心力衰竭防治的新策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d00a/10939601/a3bfd428ba9d/medi-103-e37598-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d00a/10939601/b98363bf454b/medi-103-e37598-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d00a/10939601/fc435cb8429b/medi-103-e37598-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d00a/10939601/3e12105802af/medi-103-e37598-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d00a/10939601/afa5a31887f5/medi-103-e37598-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d00a/10939601/4bdb57cb22a2/medi-103-e37598-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d00a/10939601/dbcbea355013/medi-103-e37598-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d00a/10939601/ec4c2755a987/medi-103-e37598-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d00a/10939601/a3bfd428ba9d/medi-103-e37598-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d00a/10939601/b98363bf454b/medi-103-e37598-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d00a/10939601/fc435cb8429b/medi-103-e37598-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d00a/10939601/3e12105802af/medi-103-e37598-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d00a/10939601/afa5a31887f5/medi-103-e37598-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d00a/10939601/4bdb57cb22a2/medi-103-e37598-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d00a/10939601/dbcbea355013/medi-103-e37598-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d00a/10939601/ec4c2755a987/medi-103-e37598-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d00a/10939601/a3bfd428ba9d/medi-103-e37598-g008.jpg

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Determinants and outcomes of mitochondrial dynamics.线粒体动力学的决定因素及结果
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Omentin1 ameliorates myocardial ischemia-induced heart failure via SIRT3/FOXO3a-dependent mitochondrial dynamical homeostasis and mitophagy.
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