Center of Innovation in Long Term Services and Supports, VA Providence Healthcare System, Providence, RI, USA; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA.
Medical Service, VA Providence Healthcare System, Providence, RI, USA.
J Psychiatr Res. 2024 May;173:58-63. doi: 10.1016/j.jpsychires.2024.03.004. Epub 2024 Mar 11.
Medical comorbidity, particularly cardiovascular diseases, contributes to high rates of hospital admission and early mortality in people with schizophrenia. The 30 days following hospital discharge represents a critical period for mitigating adverse outcomes. This study examined the odds of successful community discharge among Veterans with schizophrenia compared to those with major affective disorders and those without serious mental illness (SMI) after a heart failure hospital admission. Data for Veterans hospitalized for heart failure were obtained from the Veterans Health Administration (VHA) and Centers for Medicare & Medicaid Services between 2011 and 2019. Psychiatric diagnoses and medical comorbidities were assessed in the year prior to hospitalization. Successful community discharge was defined as remaining in the community without hospital readmission, death, or hospice for 30 days after hospital discharge. Logistic regression analyses adjusting for relevant factors were used to examine whether individuals with a schizophrenia diagnosis showed lower odds of successful community discharge versus both comparison groups. Out of 309,750 total Veterans in the sample, 7377 (2.4%) had schizophrenia or schizoaffective disorder and 32,472 (10.5%) had major affective disorders (bipolar disorder or recurrent major depressive disorder). Results from adjusted logistic regression analyses demonstrated significantly lower odds of successful community discharge for Veterans with schizophrenia compared to the non-SMI (Odds Ratio [OR]: 0.63; 95% Confidence Interval [CI]: 0.60, 0.66) and major affective disorders (OR: 0.65, 95%; CI: 0.62, 0.69) groups. Intervention efforts should target the transition from hospital to home in the subgroup of Veterans with schizophrenia.
医疗合并症,特别是心血管疾病,导致精神分裂症患者的住院率和早期死亡率居高不下。在出院后的 30 天内,是减轻不良后果的关键时期。本研究比较了退伍军人中精神分裂症患者与心境障碍和无严重精神疾病(SMI)患者在心力衰竭住院后成功社区出院的几率。退伍军人心力衰竭住院的数据来自退伍军人事务部(VHA)和医疗保险和医疗补助服务中心(Centers for Medicare & Medicaid Services),时间范围为 2011 年至 2019 年。在住院前一年评估了精神科诊断和合并症。成功的社区出院定义为在出院后 30 天内留在社区中,没有再次住院、死亡或入住临终关怀。使用调整了相关因素的逻辑回归分析来检查精神分裂症诊断患者与两个对照组相比,其成功社区出院的可能性是否较低。在样本中的 309750 名退伍军人中,有 7377 名(2.4%)患有精神分裂症或分裂情感障碍,32472 名(10.5%)患有心境障碍(双相情感障碍或复发性重度抑郁症)。调整后的逻辑回归分析结果表明,与非 SMI(比值比[OR]:0.63;95%置信区间[CI]:0.60,0.66)和心境障碍(OR:0.65,95%CI:0.62,0.69)相比,退伍军人患精神分裂症患者成功社区出院的可能性显著较低。干预措施应针对精神分裂症退伍军人亚组从医院到家庭的过渡。