King's College London (Institute of Psychiatry, Psychology, and Neuroscience),UK.
Biomedical Research Centre Nucleus, South London and Maudsley NHS Foundation Trust,London,UK.
Psychol Med. 2018 Dec;48(16):2676-2683. doi: 10.1017/S0033291718000284. Epub 2018 Feb 28.
Serious mental illness (SMI, including schizophrenia, schizoaffective disorder, and bipolar disorder) is associated with worse general health. However, admissions to general hospitals have received little investigation. We sought to delineate frequencies of and causes for non-psychiatric hospital admissions in SMI and compare with the general population in the same area.
Records of 18 380 individuals with SMI aged ⩾20 years in southeast London were linked to hospitalisation data. Age- and gender-standardised admission ratios (SARs) were calculated by primary discharge diagnoses in the 10th edition of the World Health Organization International Classification of Diseases (ICD-10) codes, referencing geographic catchment data.
Commonest discharge diagnosis categories in the SMI cohort were urinary conditions, digestive conditions, unclassified symptoms, neoplasms, and respiratory conditions. SARs were raised for most major categories, except neoplasms for a significantly lower risk. Hospitalisation risks were specifically higher for poisoning and external causes, injury, endocrine/metabolic conditions, haematological, neurological, dermatological, infectious and non-specific ('Z-code') causes. The five commonest specific ICD-10 diagnoses at discharge were 'chronic renal failure' (N18), a non-specific code (Z04), 'dental caries' (K02), 'other disorders of the urinary system' (N39), and 'pain in throat and chest' (R07), all of which were higher than expected (SARs ranging 1.57-6.66).
A range of reasons for non-psychiatric hospitalisation in SMI is apparent, with self-harm, self-neglect and/or reduced healthcare access, and medically unexplained symptoms as potential underlying explanations.
严重精神疾病(SMI,包括精神分裂症、分裂情感障碍和双相情感障碍)与较差的总体健康状况有关。然而,综合性医院的入院情况却很少受到关注。我们试图阐明 SMI 患者非精神科住院的频率和原因,并与同一地区的普通人群进行比较。
将伦敦东南部 18380 名年龄 ⩾20 岁的 SMI 患者的记录与住院数据相关联。通过 10 版世界卫生组织国际疾病分类(ICD-10)代码的主要出院诊断计算年龄和性别标准化入院率(SAR),并参考地理覆盖数据。
SMI 队列中最常见的出院诊断类别是泌尿系统疾病、消化系统疾病、未分类症状、肿瘤和呼吸系统疾病。除肿瘤的风险显著降低外,大多数主要类别中的 SAR 均升高。中毒和外部原因、损伤、内分泌/代谢疾病、血液学、神经病学、皮肤病学、传染病和非特异性(“Z 代码”)原因的住院风险明显更高。出院时最常见的五个特定 ICD-10 诊断是“慢性肾衰竭”(N18)、非特异性代码(Z04)、“龋齿”(K02)、“其他泌尿系统疾病”(N39)和“咽喉和胸部疼痛”(R07),所有这些诊断的 SAR 均高于预期(范围为 1.57-6.66)。
SMI 患者非精神科住院的原因多种多样,可能包括自我伤害、自我忽视和/或医疗服务获取减少以及无法解释的医学症状等潜在原因。