David Grant USAF Medical Center, Travis Air Force Base, CA, USA.
Mountain Home Air Force Base, ID, USA.
Am Fam Physician. 2020 Feb 15;101(4):213-220.
Cerebral palsy, which occurs in two to three out of 1,000 live births, has multiple etiologies resulting in brain injury that affects movement, posture, and balance. The movement disorders associated with cerebral palsy are categorized as spasticity, dyskinesia, ataxia, or mixed/other. Spasticity is the most common movement disorder, occurring in 80% of children with cerebral palsy. Movement disorders of cerebral palsy can result in secondary problems, including hip pain or dislocation, balance problems, hand dysfunction, and equinus deformity. Diagnosis of cerebral palsy is primarily clinical, but magnetic resonance imaging can be helpful to confirm brain injury if there is no clear cause for the patient's symptoms. Once cerebral palsy has been diagnosed, an instrument such as the Gross Motor Function Classification System can be used to evaluate severity and treatment response. Treatments for the movement disorders associated with cerebral palsy include intramuscular onabotulinumtoxinA, systemic and intrathecal muscle relaxants, selective dorsal rhizotomy, and physical and occupational therapies. Patients with cerebral palsy often also experience problems unrelated to movement that need to be managed into adulthood, including cognitive dysfunction, seizures, pressure ulcers, osteoporosis, behavioral or emotional problems, and speech and hearing impairment.
脑瘫发生于每 1000 例活产儿中的 2 至 3 例,其病因众多,可导致脑损伤,从而影响运动、姿势和平衡。脑瘫相关的运动障碍可分为痉挛、运动障碍、共济失调或混合/其他类型。痉挛是最常见的运动障碍,发生于 80%的脑瘫患儿。脑瘫的运动障碍可导致继发性问题,包括髋痛或脱位、平衡问题、手功能障碍和马蹄内翻畸形。脑瘫的诊断主要基于临床,但如果患者的症状没有明确病因,磁共振成像(MRI)可有助于确认脑损伤。一旦确诊脑瘫,可使用粗大运动功能分类系统等工具评估严重程度和治疗反应。与脑瘫相关的运动障碍的治疗方法包括肌肉内注射肉毒毒素 A、全身和鞘内肌肉松弛剂、选择性脊神经后根切断术,以及物理治疗和职业治疗。脑瘫患者在成年后还经常出现与运动无关的问题,包括认知功能障碍、癫痫、压疮、骨质疏松症、行为或情绪问题以及言语和听力障碍。