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Circulation. 2024 Jan 2;149(1):e1-e156. doi: 10.1161/CIR.0000000000001193. Epub 2023 Nov 30.
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Stroke prevention in atrial fibrillation.心房颤动的卒中预防。
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Visceral artery aneurysms: Incidence, management, and outcome analysis in a tertiary care center over one decade.内脏动脉瘤:一家三级医疗中心十年间的发病率、治疗及结局分析
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Warfarin-induced gastric intramural hematoma.华法林所致胃壁内血肿。
Rev Assoc Med Bras (1992). 2014 Jan-Feb;60(1):16-7. doi: 10.1590/1806-9282.60.01.005.
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Minor bleeds alert for subsequent major bleeding in patients using vitamin K antagonists.维生素 K 拮抗剂使用者发生随后的大出血时需警惕轻微出血。
Br J Haematol. 2011 May;153(4):508-14. doi: 10.1111/j.1365-2141.2011.08656.x. Epub 2011 Mar 21.
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Gastric intramural hematoma: a case report and literature review.胃壁内血肿:一例报告及文献综述
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Hemorrhagic complications of anticoagulant and thrombolytic treatment: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).抗凝和溶栓治疗的出血并发症:美国胸科医师学会循证临床实践指南(第8版)
Chest. 2008 Jun;133(6 Suppl):257S-298S. doi: 10.1378/chest.08-0674.
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Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).维生素K拮抗剂的药理学与管理:美国胸科医师学会循证临床实践指南(第8版)
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9
Spontaneous intramural gastric haematoma as a complication of oral anticoagulant therapy mimicking acute myocardial infarction.自发性胃壁内血肿作为口服抗凝治疗的并发症,酷似急性心肌梗死。
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10
A giant intramural gastric hematoma successfully treated by transcatheter arterial embolization.经导管动脉栓塞术成功治疗巨大胃壁内血肿。
Intern Med. 2000 Mar;39(3):231-4. doi: 10.2169/internalmedicine.39.231.

华法林诱导自发性胃壁内血肿致心悸。

Warfarin induced spontaneous gastric intramural haematoma presenting with palpitations.

机构信息

Internal Medicine, Texas Tech University Health Sciences Center, School of Medicine Permian Basin, Odessa, Texas, USA

Internal Medicine, Texas Tech University Health Sciences Center, School of Medicine Permian Basin, Odessa, Texas, USA.

出版信息

BMJ Case Rep. 2024 Mar 15;17(3):e259539. doi: 10.1136/bcr-2023-259539.

DOI:10.1136/bcr-2023-259539
PMID:38490703
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10946342/
Abstract

Spontaneous gastric intramural haematoma is an uncommon complication associated with anticoagulant therapy. A patient receiving chronic warfarin for paroxysmal atrial fibrillation was admitted due to atrial fibrillation with rapid ventricular response (RVR). An incidental intra-abdominal mass was detected on a CT scan. Following the initiation of the amiodarone infusion, the patient experienced bleeding attributed to warfarin-amiodarone-induced coagulopathy, with no identifiable bleeding source. Subsequent CT scans revealed an enlargement of the intra-abdominal mass, suggesting gastric intramural haematoma. After coagulopathy reversal, the haematoma is managed conservatively. Our case underscores the potential for incidental bleeding even when the international normalised ratio is within the normal range in patients on chronic warfarin therapy. When managing such patients with atrial fibrillation with RVR, physicians should maintain a high index of suspicion for bleeding, emphasising the importance of prompt coagulopathy reversal.

摘要

自发性胃壁内血肿是一种罕见的与抗凝治疗相关的并发症。一名因阵发性心房颤动接受慢性华法林治疗的患者因快速心室反应(RVR)而入院。腹部 CT 扫描发现偶然的腹腔内肿块。胺碘酮输注开始后,患者出现出血归因于华法林-胺碘酮诱导的凝血障碍,无明显出血源。随后的 CT 扫描显示腹腔内肿块增大,提示胃壁内血肿。凝血障碍纠正后,血肿保守治疗。我们的病例强调了即使在慢性华法林治疗患者的国际标准化比值在正常范围内,也可能发生意外出血。当处理伴有 RVR 的心房颤动患者时,医生应保持高度警惕出血,并强调及时纠正凝血障碍的重要性。