Ruggiero G, Santarpia L
Ann Sclavo. 1978 Nov-Dec;20(6):793-308.
This paper deals with features and problems of congenital rubella and perspectives in the prevention of this infection. We discussed the factors determining whether or not the maternal infection will involve the fetus, the pathogenesis and the clinical aspects of congenital rubella, the epidemiological importance of infected infants who may be contagious for long periods of time, the problems encountered in diagnosis. The efficacy of the active immunization programs, the data available in the literature on inadvertent vaccination of pregnant women, the restriction in the prophylactic use of immunoglobulins are also reported. The great importance of the premarital serological test for women is stressed.
本文探讨了先天性风疹的特征与问题以及预防该感染的前景。我们讨论了决定母体感染是否会累及胎儿的因素、先天性风疹的发病机制与临床症状、长期具有传染性的感染婴儿的流行病学意义、诊断中遇到的问题。还报告了主动免疫计划的效果、文献中关于孕妇意外接种疫苗的现有数据、免疫球蛋白预防性使用的限制。强调了对女性进行婚前血清学检测的重要性。