Department of Radiation Oncology, E-Da Cancer Hospital, I-Shou University, Kaohsiung, Taiwan.
Department of Medical Imaging and Radiological Sciences, College of Medical Science and Technology, I-Shou University, Kaohsiung, Taiwan.
Int J Hematol. 2024 Jun;119(6):728-735. doi: 10.1007/s12185-024-03746-8. Epub 2024 Mar 17.
The incidence of T-cell lymphoma (TCL) has been continually increasing in Taiwan and the United States (US) in recent years. This epidemiological study using population-based registry data aimed to determine the incidence patterns of common subtypes of TCL in Taiwan from 2008-2020 and compare them with those in the US and the Asian/Pacific Islander (API) population. Subtypes included angioimmunoblastic T-cell lymphoma (AITL); extranodal NK/T-cell lymphoma, nasal or other type (ENKTL); peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS); and anaplastic large cell lymphoma (ALCL). The total number of patients newly diagnosed with TCL during 2008-2020 was 4477, 3171, and 48,889 in Taiwan, API, and the US, respectively. Except the incidence rate of AITL in Taiwan, the incidence rates of these common TCL subtypes showed downward trends in all studied populations. There was also a significant increase in the relative frequency of AITL among TCL in Taiwan, with an annual percent change of 4.44 (p < 0.001), from 8.44% in 2002 to 20.63% in 2020. The rapid development of diagnostics may be the main factor contributing to this rise in incidence.
近年来，台湾和美国（US）的 T 细胞淋巴瘤（TCL）发病率持续上升。本项基于人群的注册数据的流行病学研究旨在确定 2008-2020 年台湾常见 TCL 亚型的发病模式，并将其与美国和亚洲/太平洋岛民（API）人群进行比较。亚型包括血管免疫母细胞性 T 细胞淋巴瘤（AITL）；结外 NK/T 细胞淋巴瘤，鼻型或其他型（ENKTL）；外周 T 细胞淋巴瘤，非特指型（PTCL-NOS）；和间变性大细胞淋巴瘤（ALCL）。2008-2020 年期间，台湾、API 和美国分别有 4477、3171 和 48889 例新诊断 TCL 患者。除了台湾 AITL 的发病率外，所有研究人群中这些常见 TCL 亚型的发病率均呈下降趋势。台湾 TCL 中 AITL 的相对频率也显著增加，年变化百分比为 4.44（p<0.001），从 2002 年的 8.44%增加到 2020 年的 20.63%。诊断技术的快速发展可能是导致发病率上升的主要因素。
