Department of Cardiology, Iwate Prefectural Central Hospital, Japan.
Department of Pathology, Iwate Prefectural Central Hospital, Japan.
Intern Med. 2024;63(6):821-827. doi: 10.2169/internalmedicine.2200-23. Epub 2024 Mar 15.
Myocardial calcification in myocarditis is rare and may be linked to poor outcomes. We herein report a case of fulminant myocarditis with massive myocardial calcification and its pathological outcomes at autopsy. A 49-year-old man experienced chest pain and was diagnosed with acute myocarditis. His cardiac function did not recover despite mechanical circulatory support in combination with V-A extracorporeal membrane oxygenation and IMPELLA CP. He eventually developed sepsis and gastrointestinal bleeding and died on day 27. Diffuse myocardial calcification was observed on computed tomography at autopsy. The pathological autopsy depicted that calcification filled every myocardial cell in the left ventricle.
心肌炎中的心肌钙化较为罕见,且可能与不良结局相关。在此,我们报告一例暴发性心肌炎伴大量心肌钙化及尸检病理结果。一名 49 岁男性因胸痛就诊,被诊断为急性心肌炎。尽管采用机械循环支持联合 V-A 体外膜肺氧合和 IMPELLA CP 治疗,但其心功能仍未恢复。患者最终发生脓毒症和胃肠道出血,并于第 27 天死亡。尸检时 CT 显示弥漫性心肌钙化。病理尸检显示左心室的每个心肌细胞内均有钙化。