Kimura Yuki, Seguchi Osamu, K Kono Atsushi, Matsumoto Manabu, Kumai Yuto, Kuroda Kensuke, Nakajima Seiko, Watanabe Takuya, Matsumoto Yorihiko, Fukushima Satsuki, Yanase Masanobu, Fujita Tomoyuki, Ishibashi-Ueda Hatsue, Kobayashi Junjiro, Fukushima Norihide
Department of Transplant Medicine, National Cerebral and Cardiovascular Center, Japan.
Department of Radiology, National Cerebral and Cardiovascular Center, Japan.
Intern Med. 2019 May 1;58(9):1283-1286. doi: 10.2169/internalmedicine.2039-18. Epub 2018 Dec 18.
The natural course of myocardial calcification is unclear. We herein report a case of massive biventricular myocardial calcification associated with fulminant myocarditis and present its natural course. The patient was a 15-year-old boy. Massive calcification was detected in both ventricles on computed tomography several months after left ventricular assist device placement. Although the calcification gradually regressed, the patient's cardiac function did not recover, and he underwent heart transplantation after a waiting period of 3 years. A histological examination revealed severe fibrosis in both ventricles of the original heart. Myocardial calcification might suggest severe myocardial inflammation and injury in cases of fulminant myocarditis.
心肌钙化的自然病程尚不清楚。我们在此报告一例与暴发性心肌炎相关的双心室大量心肌钙化病例，并展示其自然病程。患者为一名15岁男孩。在植入左心室辅助装置数月后的计算机断层扫描中，双侧心室均检测到大量钙化。尽管钙化逐渐消退，但患者的心脏功能并未恢复，在等待3年后接受了心脏移植。组织学检查显示原心脏的双侧心室均有严重纤维化。在暴发性心肌炎病例中，心肌钙化可能提示严重的心肌炎症和损伤。
