Bourgain R H, Andries R, Finne E
Arch Int Pharmacodyn Ther. 1979 May;239(1):161-3.
Flurbiprofen, a cyclooxygenase inhibitor, and tranylcypromine, a PGI2 synthetase inhibitor, in topical superfusion over an arterial segment respectively decrease and increase ADP-induced local white platelet thrombus formation. Superfusion of the arterial segment with PGI2 demonstrates a dose-response related inhibition of ADP-induced thrombosis.
氟比洛芬(一种环氧化酶抑制剂)和反苯环丙胺(一种前列环素合成酶抑制剂)分别经动脉节段局部灌流时,会降低和增加由二磷酸腺苷诱导的局部白色血小板血栓形成。用前列环素对动脉节段进行灌流显示出对二磷酸腺苷诱导的血栓形成呈剂量反应相关的抑制作用。