Salisbury R E, Bevin A G, Dingeldein G P, Grisham J
Arch Surg. 1979 Oct;114(10):1188-92. doi: 10.1001/archsurg.1979.01370340094016.
A polyurethane foam (Lyofoam) has been reported to accelerate epithelization of a wound. The purpose of this study was to evaluate its efficacy as a donor-site dressing for thermally injured patients. Thus, partial-thickness injuries were made in ten pigs and covered with Lyofoam, Xeroform, Telfa, Scarlet Red, and fine-mesh gauze. Gross and histologic examinations failed to show accelerated healing under the Lyofoam dressing but did show that Scarlet Red covered donor sites healed the fastest. On clinical evaluation, nine patients only showed that Lyofoam separated earlier from the underlying wound but there was no evidence to suggest that the wound was more mature than that covered with fine-mesh gauze.
据报道，一种聚氨酯泡沫材料（Lyofoam）可加速伤口上皮形成。本研究的目的是评估其作为热损伤患者供皮区敷料的疗效。因此，在十头猪身上造成了浅度烧伤，并分别用Lyofoam、黄碘纱布、特氟纶、猩红溶液和细网纱布覆盖。大体和组织学检查未能显示Lyofoam敷料下伤口愈合加速，但显示用猩红溶液覆盖的供皮区愈合最快。在临床评估中，九名患者仅显示Lyofoam比深层伤口分离更早，但没有证据表明该伤口比用细网纱布覆盖的伤口更成熟。
