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由恶臭假单胞菌和微杆菌引起的持续性菌血症:一例报告。

Persistent bacteremia caused by Ralstonia pickettii and Microbacterium: a case report.

机构信息

Department of Laboratory Medicine, Daqing Oilfield General Hospital, Daqing, China.

出版信息

BMC Infect Dis. 2024 Mar 18;24(1):327. doi: 10.1186/s12879-024-09228-w.

Abstract

BACKGROUND

Ralstonia pickettii is a low virulent, gram-negative bacillus that is rarely associated with human infections and may cause bacteremia. Microbacterium species are gram-positive coryneforms that are generally considered as a contaminant in Gram staining of blood cultures, especially when the time to positivity is longer than 48 h. Both these bacterial species are emerging opportunistic pathogens that may occasionally cause serious infections and even life-threatening health conditions.

CASE PRESENTATION

Here, we report the case of a patient with bacteremia caused by both R. pickettii and Microbacterium. We advocate for providers to order rapid antibiotic susceptibility testing, since our patient's suffered two kinds of rare pathogens with the opposite of drug sensitivity results to imipenem.

CONCLUSIONS

Our case present a patient suffered septic shock caused by R. pickettii and Microbacterium. Improving the antibiotic management based on the result of antimicrobial susceptibility tests is the key of successful treatment.

摘要

背景

恶臭假单胞菌是一种低毒的革兰氏阴性杆菌,很少与人类感染有关,可能引起菌血症。微杆菌属是革兰氏阳性棒状杆菌,通常被认为是血培养革兰氏染色的污染菌,尤其是阳性时间超过 48 小时时。这两种细菌都是新出现的机会性病原体,偶尔会引起严重感染,甚至危及生命的健康状况。

病例介绍

在这里,我们报告了一例由恶臭假单胞菌和微杆菌引起的菌血症患者。我们主张为患者提供快速抗生素药敏试验,因为我们的患者感染了两种罕见的病原体,对亚胺培南的药敏结果相反。

结论

我们的病例报告了一例由恶臭假单胞菌和微杆菌引起的感染性休克患者。根据抗菌药物敏感性试验结果改善抗生素管理是成功治疗的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c97/10949731/8ec97bf0b4e8/12879_2024_9228_Fig2_HTML.jpg

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