Clinical Diabetes, Appetite and Metabolism Laboratory, Garvan Institute of Medical Research, Sydney, NSW, Australia; Department of Diabetes and Endocrinology, St Vincent's Hospital, Sydney, NSW, Australia; School of Clinical Medicine, UNSW Medicine & Health, St Vincent's Healthcare Clinical Campus, Faculty of Medicine, UNSW Sydney, Sydney, NSW, Australia.
Department of Diabetes and Endocrinology, Royal Melbourne Hospital, Melbourne, VIC, Australia.
Diabetes Metab Syndr. 2024 Mar;18(3):102986. doi: 10.1016/j.dsx.2024.102986. Epub 2024 Mar 14.
To improve the diagnosis and classification of patients who fail to satisfy current type 1 diabetes diagnostic criteria.
Review of the literature and current diagnostic guidelines.
We propose a novel, clinically useful classification based on islet autoantibody status and non-fasting C-peptide levels. Notably, we discuss the subgroup of latent autoimmune diabetes in the young and propose a new subgroup classification of autoantibody negative type 1 diabetes in remission.
A novel classification system is proposed. Further work is needed to accurately diagnose and manage minority type 1 diabetes subgroups.
改进不符合当前 1 型糖尿病诊断标准的患者的诊断和分类。
文献回顾和当前诊断指南。
我们提出了一种基于胰岛自身抗体状态和空腹 C 肽水平的新的、临床有用的分类方法。值得注意的是，我们讨论了年轻起病的成人隐匿性自身免疫糖尿病亚组，并提出了缓解期自身抗体阴性 1 型糖尿病的新亚组分类。
提出了一种新的分类系统。需要进一步的工作来准确诊断和管理少数 1 型糖尿病亚组。
