活髓切断术与牙髓摘除术治疗恒前牙龋源性露髓的随机对照研究。

Pulpotomy versus pulpectomy in carious vital pulp exposure in primary incisors: a randomized controlled trial.

机构信息

Researcher of Pediatric Dentistry, Orthodontics and Pediatric Dentistry Department, National Research Centre, Elbuhouth st, Dokki, Cairo, 12622, Egypt.

Pediatric Dentistry and Dental Public Health, Faculty of Dentistry, Cairo University, Dokki, Egypt.

出版信息

BMC Oral Health. 2024 Mar 20;24(1):354. doi: 10.1186/s12903-024-04116-w.

DOI:10.1186/s12903-024-04116-w

PMID:38504243

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10953279/

Abstract

BACKGROUND

Pulpotomy as a minimally invasive pulp therapy technique is the treatment of choice for carious pulp exposures, however many pediatric dentists perform pulpectomies in vital primary incisors. The aim of this split mouth randomized controlled study was to compare formocresol pulpotomy and zinc-oxide and eugenol pulpectomy in the treatment of vital pulp exposure in primary incisors.

METHODS

Contralateral pairs of incisors were randomly assigned to receive pulpotomy or pulpectomy in children aging from 18 to 66 months old and were followed up for 12 months.

RESULTS

39 pairs of incisors were included. Clinical and radiographical success rates showed no statistical significant difference (p = 1, p = 0.8 respectively). Relative risk measures for clinical success rates (RR = 1.03, 95%CI 0.87 to 1.23) and for radiographic success rates (RR = 1.03, 95%CI 0.83 to 1.29) with CIs including number one showing no difference between the two groups. The Survival rate using Kaplan-Meier survival analysis score showed 82% for pulpotomy and 74% for pulpectomy at 12 months (P = 0.2).

CONCLUSIONS

Both pulpotomy and pulpectomy techniques can be used successfully in the treatment of carious vital pulp exposure in primary incisors.

TRIAL REGISTRATION

The trial was retrospectively registered in Clinicaltrials .gov with this identifier NCT05589025 on 21/10/2022.

摘要

背景

活髓切断术作为一种微创牙髓治疗技术，是治疗龋源性牙髓暴露的首选方法，然而许多儿童牙医在活髓恒前牙中进行牙髓切除术。本研究采用随机对照的split-mouth 设计，旨在比较甲醛甲酚活髓切断术和氧化锌丁香油糊剂牙髓切除术治疗恒前牙活髓暴露的疗效。

方法

将 18-66 个月龄儿童的双侧恒切牙随机分为活髓切断术或牙髓切除术组，并进行 12 个月的随访。

结果

共纳入 39 对切牙。临床和影像学成功率无统计学差异（p=1，p=0.8）。临床成功率的相对危险度（RR=1.03，95%CI 0.87-1.23）和影像学成功率的相对危险度（RR=1.03，95%CI 0.83-1.29）的置信区间（CI）均包含 1，表明两组间无差异。Kaplan-Meier 生存分析评分显示，活髓切断术组的 12 个月生存率为 82%，牙髓切除术组为 74%（P=0.2）。