Manji Ali, Basiri Reza, Harton Francois, Rommens Kenton, Manji Karim
Zivot Limb Preservation Centre, Alberta Health Services, Calgary, Alberta, Canada.
Department of Surgery, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Int J Low Extrem Wounds. 2025 Mar;24(1):117-123. doi: 10.1177/15347346241238458. Epub 2024 Mar 20.
This study evaluated the toe and flow model (TFM), a limb preservation program led by podiatric surgeons in Alberta, Canada, for its impact on hospitalization rates and length of stay (LOS) in patients with diabetic foot complication (DFC). Diabetes, a leading cause of non-traumatic lower extremity amputations (LEAs) in Canada, often results in diabetic foot ulcers (DFUs), a major cause of infection, amputation, and hospitalization. TFM has reportedly reduced amputation rates by 39% to 56%.
The study analyzed Alberta's health database from 2007 to 2017, focusing on diabetes patients aged 20 and above. It included patients with various DFCs and compared outcomes in regions using TFM and standard of care (SOC). The study also examined data from two major cities, one with TFM and the other without, including rural referrals to Calgary and Edmonton. The data were normalized for the diabetic population and analyzed using a standard Student's -test.
TFM regions showed significantly lower hospitalization rates ( = 1.22E-12) than SOC regions. Over 11 years, TFM maintained lower average and median LOS by 0.13 and 0.26 days, respectively. TFM access reduced hospitalization risk by up to 30%, and patients in TFM regions had a 21% shorter LOS compared to SOC regions.
Despite similar demographics and healthcare systems, the TFM region benefited from a dedicated multidisciplinary program and comprehensive limb preservation services. The study shows that TFM effectively reduces hospitalizations and LOS for DFCs, with significantly better outcomes in the TFM region than in SOC regions.
本研究评估了由加拿大艾伯塔省足病外科医生主导的保肢计划——足趾与血流模型(TFM),该计划对糖尿病足并发症(DFC)患者的住院率和住院时长(LOS)的影响。糖尿病是加拿大非创伤性下肢截肢(LEA)的主要原因,常导致糖尿病足溃疡(DFU),而DFU是感染、截肢和住院的主要原因。据报道,TFM已将截肢率降低了39%至56%。
该研究分析了2007年至2017年艾伯塔省的健康数据库,重点关注20岁及以上的糖尿病患者。研究纳入了患有各种DFC的患者,并比较了采用TFM和标准护理(SOC)的地区的治疗结果。该研究还检查了来自两个主要城市的数据,一个采用TFM,另一个未采用,包括农村地区转诊至卡尔加里和埃德蒙顿的患者。数据针对糖尿病患者群体进行了标准化处理,并使用标准的学生t检验进行分析。
TFM地区的住院率显著低于SOC地区(= 1.22E - 12)。在11年的时间里,TFM的平均住院时长和中位住院时长分别降低了0.13天和0.26天。采用TFM可将住院风险降低多达30%,与SOC地区相比,TFM地区的患者住院时长缩短了21%。
尽管人口统计学特征和医疗保健系统相似,但TFM地区受益于专门的多学科计划和全面的保肢服务。该研究表明,TFM能有效降低DFC患者的住院率和住院时长,TFM地区的治疗效果明显优于SOC地区。