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一项多中心横断面观察性研究,旨在分析中度高海拔对眼部健康的影响。

A Multicentric Cross-Sectional Observational Study to Analyze the Effects of Moderate High Altitude on Ocular Health.

作者信息

Maria Vibhuti, Kumar Khanna Sanat, Chaudhary Richa, Maheshwari Saurabh

机构信息

Department of Ophthalmology, Military Hospital Shimla, Shimla, India.

Department of Surgery, Military Hospital Shimla, Shimla, India.

出版信息

Beyoglu Eye J. 2024 Mar 1;9(1):48-54. doi: 10.14744/bej.2023.81557. eCollection 2024.

Abstract

OBJECTIVES

Prolonged exposure to hypoxia at high altitudes can affect the eyes through various mechanisms, culminating in reduced vision. Multiple studies on this subject have focused on the ocular effects of high altitude on intraocular pressure (IOP), corneal thickness, and the retina. However, there is a lack of literature on the effects of 'moderate high altitude (2000-3000 m)' on the eyes. Hence, we designed our study to determine the impact of moderate high altitude on the eyes.

METHODS

We recruited two age and gender-matched groups of 250 research participants, each at moderate high altitude (Group A) and plains (Group B), respectively, to determine the effects of moderate high altitude on ocular health, if any.

RESULTS

We found a statistically significant increase in dry eye in Group A. We also found four cases of central serous retinopathy and one case of central retinal vein occlusion in Group A. There was no statistically significant change in visual acuity, IOP, or central corneal thickness.

CONCLUSION

There is a vast lacuna in the literature on this particular altitude range, and further studies are required to confirm our findings. It is also recommended that lubricant eye drops be advised as a standard prophylactic measure for all individuals traveling and staying at moderate high altitude.

摘要

目的

在高海拔地区长时间暴露于低氧环境可通过多种机制影响眼睛,最终导致视力下降。关于这一主题的多项研究集中于高海拔对眼压(IOP)、角膜厚度和视网膜的眼部影响。然而,缺乏关于“中度高海拔(2000 - 3000米)”对眼睛影响的文献。因此,我们设计了本研究以确定中度高海拔对眼睛的影响。

方法

我们招募了两组年龄和性别匹配的研究参与者,每组250人,分别处于中度高海拔地区(A组)和平原地区(B组),以确定中度高海拔对眼部健康是否有影响。

结果

我们发现A组干眼症有统计学意义的增加。我们还在A组发现了4例中心性浆液性视网膜病变和1例视网膜中央静脉阻塞。视力、眼压或中央角膜厚度无统计学意义的变化。

结论

关于这个特定海拔范围的文献存在巨大空白,需要进一步研究来证实我们的发现。还建议对所有前往并停留在中度高海拔地区的人,将润滑眼药水作为标准预防措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ca6/10944850/5c448e8d7c7f/BEJ-9-48-g001.jpg

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