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整形手术患者贫血、输血和结局的预测因素。

Predictors for anaemia, blood transfusion and outcome in plastic surgery patients.

机构信息

University of Medicine and Pharmacy "Iuliu Hatieganu" Cluj Napoca, 8 Victor Babes Street, 400012, Cluj-Napoca, Romania.

Emergency County Hospital, 3-5 Clinicilor Street, 400006, Cluj-Napoca, Romania.

出版信息

J Int Med Res. 2024 Mar;52(3):3000605241237720. doi: 10.1177/03000605241237720.

Abstract

OBJECTIVE

In patients undergoing plastic surgery, to identify specific risk factors for anaemia and use of blood products, and assess their impact on patient outcome.

METHOD

For this retrospective study, data were analysed from patients who attended the Plastic Surgery Department at our hospital over a three-year period (2018 to 2020). Adult patients who presented with traumatic injuries, oncologic patients who underwent reconstructive procedures, and patients with soft tissue infections (STIs) who required plastic surgery for tissue coverage were included. Demographic and injury data, hospital admission characteristics, surgical procedures, laboratory test results, transfusion events, and in-hospital complications were extracted from patient records.

RESULTS

Of the 350 patients included in the study, 228 (65%) presented with trauma, 76 (22%) underwent reconstructive surgery for cancers and 46 (13%) had STIs. In total, 175 (50%) patients developed anaemia, and 37 (11%) received blood transfusions; these were 20 (54%), 5 (14%), and 12 (32%) patients in the trauma, cancer and STI groups, respectively. Associated comorbidities and upper and lower limb surgery were the most significant risk factors for anaemia, while the number of surgeries and NSTIs were identified as risk factors for blood transfusions. Direct wound closure was consistently a protective factor for both anaemia and blood transfusions. Blood transfusions were independently associated with a high risk of sepsis, wound complications, and prolonged hospital stay.

CONCLUSION

While transfusions are necessary and even lifesaving in surgical patients, blood is a finite resource and its use may negatively impact patient outcome. Therefore, ongoing research must focus on providing safe and restrictive clinical practices while developing sustainable and accessible alternatives.

摘要

目的

在接受整形手术的患者中,确定贫血和用血产品的特定风险因素,并评估其对患者预后的影响。

方法

这项回顾性研究分析了在我院整形科就诊的 3 年(2018 年至 2020 年)期间的患者数据。纳入了创伤患者、接受重建手术的肿瘤患者和需要整形手术进行组织覆盖的软组织感染(STI)患者。从患者记录中提取人口统计学和损伤数据、住院特征、手术程序、实验室检查结果、输血事件和院内并发症。

结果

在纳入研究的 350 例患者中,228 例(65%)为创伤患者,76 例(22%)为癌症重建手术患者,46 例(13%)为 STI 患者。总共有 175 例(50%)患者发生贫血,37 例(11%)接受输血;创伤、癌症和 STI 组中分别有 20 例(54%)、5 例(14%)和 12 例(32%)患者发生贫血和输血。合并症和上下肢手术是贫血的最显著危险因素,而手术次数和非 STI 是输血的危险因素。直接缝合伤口始终是贫血和输血的保护因素。输血与败血症、伤口并发症和住院时间延长的高风险独立相关。

结论

虽然在外科患者中输血是必要的,甚至是救命的,但血液是有限的资源,其使用可能会对患者预后产生负面影响。因此,必须持续研究,在开发可持续和可获得的替代方法的同时,重点关注提供安全和限制性的临床实践。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/606f/10956162/040c234384f3/10.1177_03000605241237720-fig1.jpg

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