The National State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China.
Hubei Key Laboratory of Plant Pathology, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Phytopathology. 2024 Jul;114(7):1603-1611. doi: 10.1094/PHYTO-01-24-0038-R. Epub 2024 Jul 1.
Transcription factors play critical roles in diverse biological processes in fungi. XlnR, identified as a transcriptional activator that regulates the expression of the extracellular xylanase genes in fungi, has not been extensively studied for its function in fungal development and pathogenicity in rice false smut fungus . In this study, we characterized in and established that the full-length, N-terminal, and C-terminal forms have the ability to activate transcription. The study further demonstrated that plays crucial roles in various aspects of biology. Deletion of affected growth, conidiation, and stress response. mutants also exhibited reduced pathogenicity, which could be partially attributed to the reduced expression of xylanolytic genes and extracellular xylanase activity of during the infection process. Our results indicate that is involved in regulating growth, conidiation, stress response, and pathogenicity.
转录因子在真菌的多种生物学过程中发挥着关键作用。XlnR 被鉴定为一种转录激活因子，可调节真菌中细胞外木聚糖酶基因的表达，但在水稻纹枯病菌中，其在真菌发育和致病性方面的功能尚未得到广泛研究。在本研究中，我们对 进行了鉴定和功能分析，并确定全长、N 端和 C 端形式均具有转录激活能力。研究进一步表明， 在 生物学的各个方面都起着至关重要的作用。 缺失会影响生长、分生孢子形成和应激反应。 突变体的致病性也降低，这在一定程度上归因于感染过程中木聚糖酶基因表达和细胞外木聚糖酶活性的降低。我们的结果表明， 参与调节生长、分生孢子形成、应激反应和致病性。
