Berger Ori, Hornik-Lurie Tzipi, Talisman Ran
Plastic Surgery Unit, Barzilai University Hospital Medical Center, Ashkelon, Israel.
Department of Data Research at the Research Authority, Meir Medical Center, Kfar Saba, Israel.
Front Pediatr. 2024 Mar 6;12:1367550. doi: 10.3389/fped.2024.1367550. eCollection 2024.
Adolescent gynecomastia, a benign proliferation of male breast tissue, can lead to psychological issues during adolescence. The prevalence varies widely (4%-69%). The incidence peaks are during neonatal, pubertal, and senescent periods. Its affect on emotional well-being necessitates understanding and occasional intervention. This study aimed to determine the incidence of gynecomastia among male adolescents aged 12-15 years.
A retrospective cross-sectional study utilized the Clalit Health Care Services database (2008-2021) with a population of approximately 4.5 million. Participants aged 12-15 years were included if diagnosed with gynecomastia (International classification of diseases-9 code 611.1) and having a body mass index (BMI) measurement and no obesity diagnosis (ICD9 code 278.0). Data analysis included incidence rates and associations with ethnicity, age, BMI, and socioeconomic status.
531,686 participants included with an incidence of 1.08%. Of all participants, 478,140 had a BMI ≤ 25 with an incidence of 0.7%, and 0.25%-0.35% yearly, and 70% of gynecomastia patients were aged 13-14 years. The prevalence of gynecomastia differed between Jews (1.28%) and Arabs (0.67%), but the disparity diminished when socioeconomic status was considered.
This unprecedented Population study establishes a definitive rate of true pubertal gynecomastia, revealing a lower yearly incidence as compared to previous reports. The higher observed prevalence among Jewish adolescents, may be caused due to complex interactions between different influencing factors. Understanding these dynamics can aid in formulating more targeted interventions and policy strategies to address gynecomastia's affect on adolescent well-being.
青春期男性乳房肥大是男性乳腺组织的良性增生，可导致青春期出现心理问题。其患病率差异很大（4%-69%）。发病高峰出现在新生儿期、青春期和衰老期。其对情绪健康的影响需要加以了解并偶尔进行干预。本研究旨在确定12至15岁男性青少年中男性乳房肥大的发病率。
一项回顾性横断面研究利用了克拉利特医疗服务数据库（2008 - 2021年），该数据库约有450万人口。年龄在12至15岁、被诊断为男性乳房肥大（国际疾病分类-9编码611.1）且有体重指数（BMI）测量值且无肥胖诊断（ICD9编码278.0）的参与者被纳入研究。数据分析包括发病率以及与种族、年龄、BMI和社会经济地位的关联。
共纳入531,686名参与者，发病率为1.08%。在所有参与者中，478,140人的BMI≤25，发病率为0.7%，每年发病率为0.25% - 0.35%，70%的男性乳房肥大患者年龄在13至14岁。男性乳房肥大的患病率在犹太人群（1.28%）和阿拉伯人群（0.67%）之间存在差异，但在考虑社会经济地位后这种差异减小。
这项前所未有的人群研究确定了青春期男性乳房肥大的确切发病率，显示出与以往报告相比每年发病率较低。在犹太青少年中观察到的较高患病率可能是由于不同影响因素之间的复杂相互作用所致。了解这些动态情况有助于制定更有针对性的干预措施和政策策略，以应对男性乳房肥大对青少年健康的影响。
