心脏生物物理学等几何建模的当前进展。
Current progress toward isogeometric modeling of the heart biophysics.
作者信息
Torre Michele, Morganti Simone, Pasqualini Francesco S, Reali Alessandro
机构信息
Department of Civil Engineering and Architecture, University of Pavia, Via Ferrata 3, 27100 Pavia, Italy.
Department of Electrical, Computer, and Biomedical Engineering, University of Pavia, Via Ferrata 5, 27100 Pavia, Italy.
出版信息
Biophys Rev (Melville). 2023 Nov 13;4(4):041301. doi: 10.1063/5.0152690. eCollection 2023 Dec.
In this paper, we review a powerful methodology to solve complex numerical simulations, known as isogeometric analysis, with a focus on applications to the biophysical modeling of the heart. We focus on the hemodynamics, modeling of the valves, cardiac tissue mechanics, and on the simulation of medical devices and treatments. For every topic, we provide an overview of the methods employed to solve the specific numerical issue entailed by the simulation. We try to cover the complete process, starting from the creation of the geometrical model up to the analysis and post-processing, highlighting the advantages and disadvantages of the methodology.
在本文中，我们回顾了一种用于解决复杂数值模拟的强大方法——等几何分析，重点关注其在心脏生物物理建模中的应用。我们聚焦于血液动力学、瓣膜建模、心脏组织力学以及医疗设备和治疗的模拟。对于每个主题，我们概述了用于解决模拟中所涉及的特定数值问题的方法。我们试图涵盖从几何模型创建到分析和后处理的完整过程，突出该方法的优缺点。
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