Harvard Medical School, Boston, Massachusetts.
Department of Orthopaedic Surgery, Brigham and Women's Hospital, Boston, Massachusetts.
J Bone Joint Surg Am. 2024 Jun 5;106(11):976-983. doi: 10.2106/JBJS.23.00706. Epub 2024 Mar 21.
Clinical guidelines for performing total joint arthroplasty (TJA) have not been uniformly adopted in practice because research has suggested that they may foster inequities in surgical access, potentially disadvantaging minority sociodemographic groups. The aim of this study was to assess whether undergoing TJA without meeting clinical guidelines affects complication risk and leads to disparities in postoperative outcomes.
This retrospective cohort study evaluated the records of 11,611 adult patients who underwent primary TJA from January 1, 2010, to December 31, 2020, at an academic hospital network. Based on self-reported race and ethnicity, 89.5% of patients were White, 3.5% were Black, 2.9% were Hispanic, 1.3% were Asian, and 2.8% were classified as other. Patients met institutional guidelines for undergoing TJA if they had a hemoglobin A1c of <8.0% and a body mass index of <40 kg/m 2 and were not currently smoking. A logistic regression model was utilized to identify factors associated with complications, and a mixed-effects model was utilized to identify factors associated with not meeting guidelines for undergoing TJA.
During the study period, 11% (1,274) of the 11,611 adults who underwent primary TJA did not meet clinical guidelines. Compared with the group who met guidelines, the group who did not had higher proportions of Black patients (3.2% versus 6.0%; p < 0.001) and Hispanic patients (2.7% versus 4.6%; p < 0.001). An increased risk of not meeting guidelines at the time of surgery was demonstrated among Black patients (odds ratio [OR], 1.60 [95% confidence interval (CI), 1.22 to 2.10]; p = 0.001) and patients insured by Medicaid (OR, 1.75 [95% CI, 1.26 to 2.44]; p = 0.001) or Medicare (OR, 1.22 [95% CI, 1.06 to 1.41]; p = 0.007). Patients who did not meet guidelines had a higher risk of reoperation than those who met guidelines (7.7% [98] versus 5.9% [615]; p = 0.017), including a higher risk of infection-related reoperation (3.1% [40] versus 1.4% [147]; p < 0.001).
We found that patients who underwent TJA despite not meeting institutional preoperative criteria had a higher risk of postoperative complications. These patients were more likely to be from racial and ethnic minority groups, to have a lower socioeconomic status, and to have Medicare or Medicaid insurance. These findings underscore the need for surgery-related shared decision-making that is informed by evidence-based guidelines in order to reduce complication burden.
Prognostic Level III . See Instructions for Authors for a complete description of levels of evidence.
尽管临床指南建议进行全关节置换术(TJA),但实际上并未得到普遍采用,因为研究表明这些指南可能会导致手术机会的不平等,从而使少数族裔社会人口群体处于不利地位。本研究旨在评估在不符合临床指南的情况下进行 TJA 是否会影响并发症风险,并导致术后结果出现差异。
这是一项回顾性队列研究,评估了 2010 年 1 月 1 日至 2020 年 12 月 31 日期间在一家学术医院网络接受初次 TJA 的 11611 名成年患者的记录。基于自我报告的种族和民族,89.5%的患者为白人,3.5%为黑人,2.9%为西班牙裔,1.3%为亚洲人,2.8%为其他。如果患者的糖化血红蛋白<8.0%且体重指数(BMI)<40kg/m²且当前不吸烟,则符合接受 TJA 的机构指南。使用逻辑回归模型确定与并发症相关的因素,使用混合效应模型确定与不符合接受 TJA 的指南相关的因素。
在研究期间,接受初次 TJA 的 11611 名成年人中有 11%(1274 名)不符合临床指南。与符合指南的患者相比,不符合指南的患者中黑人患者(3.2%比 6.0%;p<0.001)和西班牙裔患者(2.7%比 4.6%;p<0.001)的比例更高。黑人患者(比值比[OR],1.60[95%置信区间(CI),1.22 至 2.10];p=0.001)和接受医疗补助(OR,1.75[95%CI,1.26 至 2.44];p=0.001)或医疗保险(OR,1.22[95%CI,1.06 至 1.41];p=0.007)保险的患者在手术时不符合指南的风险增加。不符合指南的患者再次手术的风险高于符合指南的患者(7.7%[98]比 5.9%[615];p=0.017),包括感染相关再次手术的风险更高(3.1%[40]比 1.4%[147];p<0.001)。
我们发现,尽管不符合机构术前标准,但仍接受 TJA 的患者术后并发症风险更高。这些患者更有可能来自少数族裔群体,社会经济地位较低,并且拥有医疗保险或医疗补助。这些发现强调需要进行基于循证指南的手术相关共同决策,以减轻并发症负担。
预后 III 级。请参阅《作者须知》,以获取完整的证据水平描述。