Department of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Institute of Basic Science, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Nano Lett. 2024 Apr 3;24(13):3930-3936. doi: 10.1021/acs.nanolett.4c00083. Epub 2024 Mar 21.
Detecting weakly adsorbing molecules via label-free surface-enhanced Raman scattering (SERS) has presented a significant challenge. To address this issue, we propose a novel approach for creating tricomponent SERS substrates using dual-rim nanorings (DRNs) made of Au, Ag, and CuO, each possessing distinct functionalities. Our method involves depositing different metals on Pt nanoring skeletons to obtain each nanoring with varying surface compositions while maintaining a similar size and shape. Next, the mixture of these nanorings is transferred into a monolayer assembly with homogeneous intermixing on a solid substrate. The surface of the CuO DRNs has dangling bonds (Cu) that facilitate the strong adsorption of carboxylates through the formation of chelating bonds, while the combination of Au and Ag DRNs significantly enhances the SERS signal intensity through a strong coupling effect. Notably, the tricomponent assemblies enable the successful SERS-based analysis of biomolecules such as amino acids, proteins, nucleobases, and nucleotides.
通过无标记表面增强拉曼散射（SERS）检测弱吸附分子一直是一个重大挑战。为了解决这个问题，我们提出了一种使用由 Au、Ag 和 CuO 制成的双环纳米环（DRN）创建三组分 SERS 基底的新方法，每个环都具有不同的功能。我们的方法涉及在 Pt 纳米环骨架上沉积不同的金属，以获得具有不同表面成分的每个纳米环，同时保持相似的尺寸和形状。然后，将这些纳米环的混合物转移到固体基底上的单层组装体中，实现均匀混合。CuO DRN 的表面具有悬空键（Cu），通过形成螯合键，有利于羧酸根的强吸附，而 Au 和 Ag DRN 的组合通过强耦合效应显著增强了 SERS 信号强度。值得注意的是，三组分组装体能够成功地基于 SERS 分析生物分子，如氨基酸、蛋白质、核苷酸碱基和核苷酸。
