Department of Infectious and Tropical Diseases, Saint Antoine Hospital, Paris, France.
Virology Department, Sorbonne University, Saint-Antoine Hospital, AP-HP, Pierre Louis Epidemiology and Public Health Institute (iPLESP), INSERM 1136, Paris, France.
Clin Infect Dis. 2024 Jul 19;79(1):196-197. doi: 10.1093/cid/ciad757.
A case of a male with human immunodeficiency virus with plasma genotyping detecting no resistance and a CRF02_AG subtype had a controlled HIV RNA on antiretroviral therapy since 2010. We introduced intramuscular therapy with cabotegravir and rilpivirine. One month later, his HIV RNA was 1500 copies/mL; genotyping found a subtype B with many mutations.
一名男性艾滋病毒感染者,2010 年开始接受抗逆转录病毒治疗,其血浆基因分型检测无耐药性,且为 CRF02_AG 亚型,HIV RNA 得到控制。我们开始采用卡替拉韦和利匹韦林进行肌内注射治疗。一个月后,他的 HIV RNA 为 1500 拷贝/毫升;基因分型发现存在多种突变的 B 亚型。