Department of Medical statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Sun Yat-sen University, Guangzhou 510080, China.
Department of Psychiatry, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China.
Compr Psychiatry. 2024 Jul;132:152472. doi: 10.1016/j.comppsych.2024.152472. Epub 2024 Mar 11.
This study aimed to explore the longitudinal associations of rumination with suicidal ideation and suicide attempts in individuals with major depressive disorder (MDD).
Participants were derived from the Depression Cohort in China study (DCC). Those who completed at least one follow-up visit during the 12 months were included in the analysis. Dimensions of rumination including brooding and reflection were each measured using five items of the Ruminative Responses Scale. Suicidal ideation was assessed using the Beck Scale for Suicide Ideation. Suicide attempts were also assessed and all were analyzed with generalized estimating equations.
Our final sample included 532 participants aged 18 to 59 years (mean [SD], 26.91 [6.94] years) consisting of 148 (27.8%) males and 384 (72.2%) females. After adjusting for temporal trend and potential confounders, individuals with higher levels of reflection were more likely to report suicidal ideation (AOR =1.11, 95% CI:1.01-1.22). However, no statistically significant association was found between brooding and suicidal ideation (AOR =1.06, 95% CI:0.96-1.17). Conversely, individuals with higher levels of brooding were more likely to report suicide attempts (AOR =1.13, 95% CI:1.02-1.24), while no statistically significant association was observed between reflection and suicide attempts (AOR =0.91, 95% CI:0.82-1.01).
Rumination reflects a disturbance in cognitive emotional processing and manifests in different dimensions. Our findings suggest that high levels of reflection and brooding may be associated with a higher likelihood of having suicidal ideation and suicide attempts, respectively. However, it should be interpreted with caution, given that effect sizes are small.
本研究旨在探讨抑郁障碍个体反刍思维与自杀意念和自杀企图的纵向关联。
参与者来自中国抑郁队列研究(DCC)。在 12 个月内至少完成一次随访的患者被纳入分析。反刍思维的两个维度,即沉思和反省,分别使用反刍思维反应量表的 5 个项目进行测量。自杀意念采用贝克自杀意念量表进行评估。自杀企图也进行了评估,所有结果均采用广义估计方程进行分析。
我们的最终样本包括 532 名年龄在 18 至 59 岁(平均[标准差],26.91[6.94]岁)的参与者,其中 148 名(27.8%)为男性,384 名(72.2%)为女性。调整时间趋势和潜在混杂因素后,反省水平较高的个体更有可能报告自杀意念(优势比[OR] =1.11,95%置信区间[CI]:1.01-1.22)。然而,沉思与自杀意念之间无统计学显著关联(OR =1.06,95% CI:0.96-1.17)。相反,沉思水平较高的个体更有可能报告自杀企图(OR =1.13,95% CI:1.02-1.24),而反省与自杀企图之间无统计学显著关联(OR =0.91,95% CI:0.82-1.01)。
反刍反映了认知情绪处理的紊乱,表现为不同的维度。我们的研究结果表明,高水平的沉思和反省可能分别与更高的自杀意念和自杀企图发生风险相关。然而,鉴于效应量较小,其解释应谨慎。