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全球和反思性沉思与经历重度抑郁发作的患者的自杀企图有关。

Global and reflective rumination are related to suicide attempts among patients experiencing major depressive episodes.

机构信息

Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, No. 264 Guangzhou Road, Nanjing, 210029, Jiangsu, China.

School of Biological Sciences & Medical Engineering, Southeast University, No. 2 Sipailou Road, Nanjing, 210096, Jiangsu, China.

出版信息

BMC Psychiatry. 2021 Feb 26;21(1):117. doi: 10.1186/s12888-021-03119-z.

Abstract

BACKGROUND

Recent attention has focused on the role of rumination in suicidality, with evidence indicating that rumination may be positively related to suicidal ideation. There remains disagreement on the nature of the relationship between rumination and suicide attempts, especially in major affective disorders. This study was designed to identify whether rumination is a risk factor for attempted suicide.

METHODS

A total of 309 patients with major depressive episodes were recruited for this study, including 170 patients with major depression and 139 patients with bipolar disorder. All participants were categorized into two groups based on a series of clinical assessments: suicide attempters (n = 87) and non-suicide attempters (n = 222). Rumination was evaluated with the Ruminative Responses Scale. A binary logistic regression analysis was carried out to evaluate the relationship between rumination and suicide attempts.

RESULTS

Both global ruminative levels and the two subtypes of rumination, brooding and reflection, were significantly higher in the suicide attempters than the non-suicide attempters. After controlling for age, current depression and anxiety symptoms, and episode frequency, it was found that global rumination and reflection (but not brooding) were positively associated with suicide attempts.

CONCLUSION

These results suggest that rumination may be a risk factor for suicide attempts and highlight the maladaptive nature of reflection in patients with major depressive episodes.

摘要

背景

近期研究关注反刍思维在自杀中的作用,有证据表明反刍思维与自杀意念呈正相关。然而,反刍思维与自杀企图之间的关系性质仍存在争议,尤其是在重性情感障碍中。本研究旨在确定反刍思维是否是自杀企图的危险因素。

方法

共招募了 309 例重性抑郁发作患者,包括 170 例重性抑郁症患者和 139 例双相情感障碍患者。所有患者均根据一系列临床评估分为两组:自杀企图者(n=87)和非自杀企图者(n=222)。采用反刍思维量表评估反刍思维。采用二元逻辑回归分析评估反刍思维与自杀企图之间的关系。

结果

自杀企图者的整体反刍水平以及沉思和反省两种反刍类型均显著高于非自杀企图者。在控制年龄、当前抑郁和焦虑症状以及发作频率后,发现整体反刍和反省(而非沉思)与自杀企图呈正相关。

结论

这些结果表明,反刍思维可能是自杀企图的一个危险因素,并突出了重性抑郁发作患者中反省的适应不良性质。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a67e/7908759/ac54f3678ebb/12888_2021_3119_Fig1_HTML.jpg

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