Department of Urology, Peking University First Hospital, Beijing, China,
Institution of Urology, Peking University, Beijing, China,
Urol Int. 2024;108(4):314-321. doi: 10.1159/000538369. Epub 2024 Mar 21.
The aim of this study was to present the surgical technique and clinical outcomes of modified ileal conduit for pelvic lipomatosis (PL).
From 2020 to 2022, we prospectively enrolled 9 patients with PL undergoing modified ileal conduit. The patient characteristics, perioperative variables, and follow-up outcomes as well as the description of surgical technique were reported.
All 9 patients successfully completed the operation. Two patients had perioperative complications of Clavien-Dindo grade I. The mean operation time and bleeding volumes were 253 ± 51.4 min and 238.9 ± 196.9 mL, with a mean postoperative follow-up time of 13.0 ± 5.6 months. The postoperative 3-month and 1-year creatinine values were significantly decreased versus the preoperative (p = 0.006 and p = 0.024). The postoperative 3-month and 1-year estimated glomerular filtration rate values were significantly increased compared with those before operation (p = 0.0002 and p = 0.018). The separation value of left renal pelvis collection system after operation was significantly reduced compared with preoperative evaluation (p = 0.023 at 3 months and p = 0.042 at 1 year) and so was the right side (p = 0.019 and p = 0.023).
Modified ileal conduit is safe and feasible for PL. A large sample cohort with long-term follow-up is needed to evaluate the clinical outcomes of PL.
本研究旨在介绍改良回肠通道术治疗骨盆脂肪过多症(PL)的手术技术和临床结果。
2020 年至 2022 年,我们前瞻性纳入了 9 例接受改良回肠通道术的 PL 患者。报告了患者特征、围手术期变量和随访结果以及手术技术描述。
9 例患者均顺利完成手术。2 例患者发生 Clavien-Dindo 分级 I 级围手术期并发症。手术时间和出血量的平均值分别为 253±51.4 分钟和 238.9±196.9 毫升,术后随访时间平均为 13.0±5.6 个月。术后 3 个月和 1 年的肌酐值明显低于术前(p=0.006 和 p=0.024)。术后 3 个月和 1 年的估算肾小球滤过率值明显高于术前(p=0.0002 和 p=0.018)。术后 3 个月和 1 年左肾盂收集系统的分离值与术前评估相比明显降低(p=0.023 和 p=0.042),右侧也是如此(p=0.019 和 p=0.023)。
改良回肠通道术治疗 PL 安全可行。需要更大的样本队列和长期随访来评估 PL 的临床结果。