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盆腔脂肪增多症与肾移植:一例报告

Pelvic lipomatosis and renal transplantation: A case report.

作者信息

Zhao Jie, Fu Ying-Xin, Feng Gang, Mo Chun-Bai

机构信息

Department of Kidney Transplant, Tianjin First Central Hospital, Tianjin 300192, China.

出版信息

World J Clin Cases. 2020 Aug 26;8(16):3548-3552. doi: 10.12998/wjcc.v8.i16.3548.

Abstract

BACKGROUND

Pelvic lipomatosis is a rare disease of unknown etiology, characterized by the overgrowth of pelvic adipose tissue that causes compression of the urinary tract including the bladder and ureters, rectum and blood vessels. The patient may progressively develop obstructive uropathy which could subsequently lead to renal failure. At present, there are no reports of renal transplantation due to uremia caused by pelvic lipomatosis. The ideal management of patients with pelvic lipomatosis after renal transplantation is not yet well-established due to the lack of literature and follow-up data.

CASE SUMMARY

We report a 37-year-old male patient with pelvic lipomatosis who received a successful living donor renal transplantation on July 22, 2015. The operation was complicated as the iliac vessels and bladder were wrapped entirely in excessive abnormal fat. The external iliac artery and vein were located using ultrasonographic guidance. The adipose tissue around the right bladder was removed as far as possible, and the graft ureter was reimplanted into the bladder, using the Lich-Gregoir technique. At 22 mo after transplantation, graft percutaneous nephrostomy was performed under ultrasonographic guidance for urinary diversion due to hydronephrosis of the graft kidney. Follow-up at four years showed that the renal allograft function was stable.

CONCLUSION

When patients with pelvic lipomatosis develop renal failure, renal transplantation could be a feasible treatment strategy.

摘要

背景

盆腔脂肪增多症是一种病因不明的罕见疾病,其特征是盆腔脂肪组织过度生长,导致包括膀胱、输尿管、直肠和血管在内的泌尿系统受压。患者可能会逐渐发展为梗阻性肾病,进而导致肾衰竭。目前,尚无因盆腔脂肪增多症导致尿毒症而进行肾移植的报道。由于缺乏文献和随访数据,肾移植后盆腔脂肪增多症患者的理想管理方法尚未明确。

病例摘要

我们报告一例37岁男性盆腔脂肪增多症患者,于2015年7月22日接受了成功的活体供肾移植。手术过程复杂,因为髂血管和膀胱完全被过多的异常脂肪包裹。在超声引导下定位髂外动脉和静脉。尽可能切除右侧膀胱周围的脂肪组织,并采用Lich-Gregoir技术将移植肾输尿管重新植入膀胱。移植后22个月,由于移植肾积水,在超声引导下对移植肾进行经皮肾造瘘术以进行尿液引流。四年后的随访显示移植肾功能稳定。

结论

当盆腔脂肪增多症患者出现肾衰竭时,肾移植可能是一种可行的治疗策略。

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