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对脊髓脊膜膨出的宫内修复的思考。

Reflections upon the intrauterine repair of myelomeningocele.

机构信息

Dep. of Neurosurgery, ASST Niguarda, Piazza Ospedale Maggiore 3, 20162, Milan, Italy.

出版信息

Childs Nerv Syst. 2024 May;40(5):1571-1575. doi: 10.1007/s00381-024-06365-0. Epub 2024 Mar 22.

Abstract

The intrauterine repair of myelomeningocele presents certain advantages and has gained widespread acceptance. It significantly reduces the incidence of Chiari-2 anomalies and hydrocephalus, and it is thought to enhance the neurologic outcome. Nevertheless, several issues remain unsettled and there are no negligible disadvantages. After working with patients with myelomeningocele for 30 years, I thought about how we currently treat them. There are ethical, organizational, neurological, obstetrical, and postnatal aspects worth discussing.

摘要

脊髓脊膜膨出的宫内修复具有一定的优势,已被广泛接受。它显著降低了 Chiari-2 畸形和脑积水的发生率,并被认为能改善神经预后。然而,仍有一些问题尚未解决,且存在不可忽视的缺点。在与脊髓脊膜膨出患者合作 30 年后,我思考了我们目前对他们的治疗方法。其中涉及伦理、组织、神经、产科和产后等方面,值得讨论。

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