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[椎间融合术治疗腰椎间盘突出症术后复发的临床研究]

[Clinical study on the treatment of postoperative recurrence of lumbar disc herniation with intervertebral fusion].

作者信息

Zheng Lian-Sheng, Li Xue-Min, Li Yu-Long

机构信息

Hepingli Hospital of Beijing, Beijing 100011, China.

出版信息

Zhongguo Gu Shang. 2024 Mar 25;37(3):235-41. doi: 10.12200/j.issn.1003-0034.20220754.

Abstract

OBJECTIVE

To explore clinical effect of different intervertebral fusion devices (cage) in treating postoperative recurrent lumbar disc herniation (LDH).

METHODS

One hundred and forty-two LDH patients with recurrence after simple intervertebral disc nucleus pulpoideectomy from January 2019 to January 2021 were retrospectively analyzed. All patients were treated with combined underchannel fixation and interbody fusion and divided into a single anatomical group,two-anatomical group and a single banana group according to types and numbers of implanted cage. There were 51 patients in a single anatomical group,included 29 males and 22 females,aged from 39 to 65 years old with an average of (53.74±5.68) years old;body mass index (BMI) ranged from 18.62 to 28.13 kg·m with an average of (22.08±2.15) kg·m;the interval between operation and recurrence ranged from 0.5 to 4.0 years with an average of (2.7±0.8) years;5 patients with L,35 patients with L and 11 patients with LS;a single anatomical cage was implanted. There were 46 patients in two-anatomical group,included 25 males and 21 females,aged from 37 to 66 years old with an average of (54.52±6.02) years old;BMI ranged from 18.25 to 28.44 kg·m with an average of (21.74±1.83) kg·m;the interval between operation and recurrence ranged from 0.5 to 5.0 years with an average of (2.7±0.9) years;4 patients with L,32 patients with L and 10 patients with LS;two-anatomical cages were implanted. There were 45 patients in a single banana group,included 22 males and 23 females,aged from 38 to 65 years old with an average of (54.49±6.45) years old;BMI ranged from 18.85 to 28.20 kg·m with an average of (21.63±1.59) kg·m;the interval between operation and recurrence ranged from 0.5 to 5.0 years with an average of (2.6±1.0) years;3 patients with L,36 patients with L and 16 patients with LS;a single banana cage was implanted. Operation time,intraoperative blood loss,incision length,postoperative incision drainage volume,hospital stay and complications among 3 groups were observed and compared. The height of intervertebral space before and after operation,curvature of lordosis and the postoperative intervertebral fusion were compared. Visual analogue scale (VAS) and Oswestry disability index (ODI) were used to evaluate degree of lumbar pain and lumbar function before operation,1 and 6 months after operation,respectively.

RESULTS

All patients among 3 groups were followed up at least 6 months,and no cases were fell out. There were no significant difference in operation time,intraoperative blood loss,incision length,postoperative incision drainage volume and hospital stay among 3 groups (>0.05). At 6 months after operation,the height of intervertebral space in two-anatomical group and a single group were [(11.08±1.78) mm,(10.95±1.62) mm],curvature of lordosis were [(12.05±1.86) °,(11.63±1.57) °],which were higher than those in a single dissection group (10.14±1.54) mm,(10.92±1.45) °,and the difference were statistically significant (<0.05). The interbody fusion rate between two-anatomical and a banana group (95.65%,95.56%) were higher than that in a single anatomical group (78.43%) at 6 months after operation (<0.05). VAS and ODI of lumbar among 3 groups were decreased at 1 and 6 months after operation (<0.05). There was no significant difference in complications among 3 groups (>0.05).

CONCLUSION

The three fusion devices could achieve significant results in treating postoperative recurrence of LDH,but the implantation of two-anatomical cage and a single banana cage are more helpful to maintain the height of intervertebral space and lordosis curvature of patients with postoperative recurrence of LDH,and obtain good intervertebral fusion results.

摘要

目的

探讨不同椎间融合器(椎间融合器)治疗腰椎间盘突出症(LDH)术后复发的临床效果。

方法

回顾性分析2019年1月至2021年1月142例单纯椎间盘髓核摘除术后复发的LDH患者。所有患者均采用通道下固定联合椎间融合治疗,根据植入椎间融合器的类型和数量分为单节段组、双节段组和单节段香蕉型组。单节段组51例,男29例,女22例,年龄39~65岁,平均(53.74±5.68)岁;体重指数(BMI)为18.62~28.13kg·m,平均(22.08±2.15)kg·m;手术至复发间隔时间为0.5~4.0年,平均(2.7±0.8)年;L3 5例,L4 35例,L5S1 11例;植入1个单节段椎间融合器。双节段组46例,男25例,女21例,年龄37~66岁,平均(54.52±6.02)岁;BMI为18.25~28.44kg·m,平均(21.74±1.83)kg·m;手术至复发间隔时间为0.5~5.0年,平均(2.7±0.9)年;L3 4例,L4 32例,L5S1 10例;植入2个双节段椎间融合器。单节段香蕉型组45例,男22例,女23例,年龄38~65岁,平均(54.49±6.45)岁;BMI为18.85~28.20kg·m,平均(21.63±1.59)kg·m;手术至复发间隔时间为0.5~5.0年,平均(2.6±1.0)年;L3 3例,L4 36例,L5S1 16例;植入1个单节段香蕉型椎间融合器。观察并比较3组患者的手术时间、术中出血量、切口长度、术后切口引流量、住院时间及并发症。比较手术前后椎间隙高度、腰椎前凸曲度及术后椎间融合情况。分别采用视觉模拟评分法(VAS)和Oswestry功能障碍指数(ODI)评估术前、术后1个月和6个月时的腰痛程度和腰椎功能。

结果

3组患者均随访至少6个月,无失访病例。3组患者的手术时间、术中出血量、切口长度、术后切口引流量及住院时间比较,差异均无统计学意义(>0.05)。术后6个月,双节段组和单节段香蕉型组的椎间隙高度分别为[(11.08±1.78)mm,(10.95±1.62)mm],腰椎前凸曲度分别为[(12.05±1.86)°,(11.63±1.57)°],均高于单节段组的(10.14±1.54)mm,(10.92±1.45)°,差异有统计学意义(<0.05)。术后6个月,双节段组和单节段香蕉型组的椎间融合率(95.65%,95.56%)高于单节段组的(78.43%),差异有统计学意义(<0.05)。3组患者术后1个月和6个月时的VAS和ODI均降低(<0.05)。3组患者的并发症发生率比较,差异无统计学意义(>0.05)。

结论

三种融合器治疗LDH术后复发均能取得显著效果,但植入双节段椎间融合器和单节段香蕉型椎间融合器更有助于维持LDH术后复发患者的椎间隙高度和腰椎前凸曲度,并获得良好的椎间融合效果。

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