Nigatu Tariku, Abraham Loko, Willems Herman, Tilaye Mesfin, Tiruneh Firew, Gebru Fantay, Tafesse Zergu, Getachew Bezawit, Bulcha Mulualem, Tewfik Sami, Alemu Tadesse
JSI Research and Training Institute Inc., Addis Ababa, Ethiopia.
JSI Research and Training Institute Inc., Boston, MA, USA.
SAGE Open Med. 2024 Mar 21;12:20503121241237115. doi: 10.1177/20503121241237115. eCollection 2024.
Immunization helps reduce morbidity and mortality attributable to severe vaccine-preventable childhood illnesses. However, vaccination coverage and the quality of immunization data remain challenging in Ethiopia. This has led to poor planning, suboptimal vaccination coverage, and the resurgence of vaccine-preventable disease outbreaks in under-immunized pocket areas. The problem is further compounded by the occurrence of the COVID-19 pandemic and the disruption of the health information system due to recurrent conflict. This study assessed the current status of the immunization service and its challenges in Ethiopia.
A mixed-methods study was conducted in three regions of Ethiopia from 21 to 31 May, 2023. A survey of administrative reports was done in a total of 69 health facilities in 14 woredas (districts). Nine KIIs were conducted at a district level among immunization coordinators selected from three regions to explore the challenges of the immunization program. Linear regression and descriptive statistics were used to analyze the quantitative data. Thematic analysis was applied to analyze the qualitative data. The findings from the qualitative data were triangulated to supplement the quantitative results.
Two-thirds (66.4%) of the children were fully vaccinated, having received all vaccines, including the first dose of the MCV1, by 12 months of age, as reported through administrative reports collected from health facility records. Catchment area population size and region were significantly associated with the number of fully immunized children ( < 0.001 and = 0.005, respectively). The vaccination dropout rates of the first to third dose of pentavalent vaccine and the first dose of pentavalent vaccine to the first dose of MCV1 were 8.6% and 7.4%, respectively. A considerable proportion of health facilities lack accurate data to calculate vaccination coverage, while most of them lack accurate data for dropout rates. Longer waiting time, interruptions in vaccine supply or shortage, inaccessibility of health facilities, internal conflict and displacement, power interruption and refrigerator breakdown, poor counseling practice, and caretakers' lack of awareness, fear of side effects, and forgetfulness were the reasons for the dropout rate and low coverage. The result also showed that internal conflict and displacement have significantly affected immunization coverage, with the worst effects seen on the most marginalized populations.
The study revealed low vaccination coverage, a high dropout rate, and poor quality of immunization data. Access and vaccination coverage among marginalized community groups (e.g., orphans and street children) were also low. Hence, interventions to address organizational, behavioral, technical, and contextual (conflict and the resulting internal displacement) bottlenecks affecting the immunization program should be addressed.
免疫接种有助于降低因严重的可通过疫苗预防的儿童疾病导致的发病率和死亡率。然而,在埃塞俄比亚,疫苗接种覆盖率和免疫数据质量仍然面临挑战。这导致了规划不善、疫苗接种覆盖率不理想,以及免疫接种率低的地区疫苗可预防疾病疫情的死灰复燃。新冠疫情的爆发以及反复冲突导致的卫生信息系统中断,使问题更加复杂。本研究评估了埃塞俄比亚免疫服务的现状及其面临的挑战。
2023年5月21日至31日,在埃塞俄比亚的三个地区进行了一项混合方法研究。对14个区(县)的69个卫生设施的行政报告进行了调查。在从三个地区选出的免疫接种协调员中,在地区一级进行了9次关键信息访谈,以探讨免疫接种计划面临的挑战。使用线性回归和描述性统计分析定量数据。应用主题分析来分析定性数据。对定性数据的结果进行三角验证,以补充定量结果。
根据从卫生设施记录中收集的行政报告,三分之二(66.4%)的儿童在12个月龄时已完全接种疫苗,即接种了所有疫苗,包括第一剂MCV1。集水区人口规模和地区与完全免疫儿童的数量显著相关(分别为<0.001和=0.005)。五价疫苗第一剂至第三剂以及五价疫苗第一剂至MCV1第一剂的疫苗接种退出率分别为8.6%和7.4%。相当一部分卫生设施缺乏计算疫苗接种覆盖率的准确数据,而其中大多数缺乏关于退出率的准确数据。等待时间过长、疫苗供应中断或短缺、卫生设施难以到达、内部冲突和流离失所、电力中断和冰箱故障、咨询服务不佳以及看护人员缺乏意识、担心副作用和遗忘是退出率和覆盖率低的原因。结果还表明,内部冲突和流离失所对免疫接种覆盖率产生了重大影响,对最边缘化人群的影响最为严重。
该研究揭示了疫苗接种覆盖率低、退出率高以及免疫数据质量差的问题。边缘化社区群体(如孤儿和街头儿童)的疫苗接种可及性和覆盖率也很低。因此,应采取干预措施,解决影响免疫接种计划的组织、行为、技术和背景(冲突及由此导致的内部流离失所)瓶颈问题。