Departments of Comparative, Diagnostic, and Population Medicine, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.
Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.
J Vet Diagn Invest. 2024 May;36(3):477-480. doi: 10.1177/10406387241239912. Epub 2024 Mar 22.
is the causative agent of lactococcosis in fish and an emerging zoonotic pathogen with high levels of antimicrobial resistance. We report a case of associated septicemia in a central bearded dragon () confirmed via whole-blood PCR and direct sequencing. Following a 30-d course of ceftazidime (20 mg/kg IM q72h), the animal's clinical condition had not resolved; leukopenia persisted, with heterophil toxic change. Coelomic ultrasound findings were consistent with preovulatory follicular stasis, folliculitis, and coelomitis. Following surgical ovariectomy and an additional 30-d course of ceftazidime, the animal's behavior and appetite returned to normal, the animal tested negative via whole-blood PCR assay, and the CBC was unremarkable. To our knowledge, with associated clinical disease has not been reported previously in a bearded dragon. We conclude that should be considered as a possible etiologic agent in cases of septicemia in bearded dragons, with the potential for zoonotic transmission warranting further investigation.
是鱼类乳球菌病的病原体，也是一种具有高水平抗菌药物耐药性的新兴人畜共患病病原体。我们报告了一例通过全血 PCR 和直接测序确诊的中央鬃狮蜥（）相关败血病病例。在接受 30 天头孢他啶（20mg/kg，肌内注射，每 72 小时 1 次）治疗后，动物的临床状况仍未改善；白细胞减少持续存在，并伴有异嗜性毒性变化。体腔超声检查结果与预排卵卵泡停滞、滤泡炎和体腔炎一致。在接受手术卵巢切除术和另外 30 天头孢他啶治疗后，动物的行为和食欲恢复正常，全血 PCR 检测呈阴性，CBC 无异常。据我们所知，以前在鬃狮蜥中没有报道过与相关的临床疾病。我们的结论是，在鬃狮蜥败血病病例中，应将视为可能的病因，具有潜在的人畜共患病传播风险，值得进一步研究。
