Stanford Byers Center for Biodesign, Stanford University, Stanford, CA, 94305, USA.
Division of Neonatology, Department of Pediatrics, Oregon Health & Science University, Portland, OR, 97239, USA.
J Perinatol. 2024 Sep;44(9):1359-1364. doi: 10.1038/s41372-024-01943-1. Epub 2024 Mar 23.
This study evaluates the effectiveness of a novel device, LifeBubble, in reducing umbilical cord catheter (UC) migration and associated complications in neonates.
A retrospective review was performed at Oregon Health & Science University's NICU (2019-2021) to compare standard adhesive securement with LifeBubble. The primary outcomes were UC migration, discontinuation due to malposition, and CLABSI incidence. Differences between groups were statistically analyzed and logistic regression used to adjust for potential confounders.
Among 118 neonates (57 LifeBubble, 61 adhesive), LifeBubble significantly reduced migration of any UC > 1 vertebral body (12.3% vs. 55.7%), including UVC migration (5.3% vs. 39.3%) and UAC migration (7.0% vs 23.0%), as well as UVC discontinuation due to malposition (5.6% vs 37.7%). The number needed to treat (NNT) to prevent one instance of UVC discontinuation is 4.
LifeBubble effectively reduces UC migration and premature discontinuation, indicating its potential to enhance neonatal care and safety.
本研究评估了一种新型装置 LifeBubble 在减少新生儿脐带导管(UC)迁移及其相关并发症方面的有效性。
在俄勒冈健康与科学大学的 NICU(2019-2021 年)进行了一项回顾性研究,比较了标准粘性固定与 LifeBubble 的效果。主要结局是 UC 迁移、因位置不当而中断以及 CLABSI 的发生率。对组间差异进行了统计学分析,并使用逻辑回归来调整潜在的混杂因素。
在 118 名新生儿(57 名使用 LifeBubble,61 名使用粘性固定)中,LifeBubble 显著降低了任何 UC 迁移>1 个椎体的发生率(12.3% vs. 55.7%),包括 UVC 迁移(5.3% vs. 39.3%)和 UAC 迁移(7.0% vs. 23.0%),以及因位置不当而导致的 UVC 中断(5.6% vs. 37.7%)。预防一次 UVC 中断所需的治疗人数(NNT)为 4。
LifeBubble 有效地减少了 UC 的迁移和过早的中断,表明它有可能增强新生儿的护理和安全性。