School of Life Sciences, Arizona State University, Tempe, AZ, 85287, United States; The Biodesign Center for Fundamental and Applied Microbiomics, Arizona State University, Tempe, AZ, 85287, United States.
The Biodesign Center for Fundamental and Applied Microbiomics, Arizona State University, Tempe, AZ, 85287, United States; Center for Evolution and Medicine, Arizona State University, Tempe, AZ, 85287, United States.
Virology. 2024 Jun;594:110064. doi: 10.1016/j.virol.2024.110064. Epub 2024 Mar 21.
Papillomaviruses (family Papillomaviridae) are non-enveloped, circular, double-stranded DNA viruses known to infect squamous and mucosal epithelial cells. In the family Papillomaviridae there are 53 genera and 133 viral species whose members infect a variety of mammalian, avian, reptilian, and fish species. Within the Antarctic context, papillomaviruses (PVs) have been identified in Adélie penguins (Pygoscelis adeliae, 2 PVs), Weddell seals (Leptonychotes weddellii, 7 PVs), and emerald notothen (Trematomus bernacchii, 1 PV) in McMurdo Sound and Ross Island in eastern Antarctica. Here we identified 13 diverse PVs from buccal swabs of Antarctic fur seals (Arctocephalus gazella, 2 PVs) and leopard seal (Hydrurga leptonyx, 3 PVs) in western Antarctica (Antarctic Peninsula), and vaginal and nasal swabs of Weddell seals (8 PVs) in McMurdo Sound. These PV genomes group into four genera representing 11 new papillomavirus types, of which five are from two Antarctic fur seals and a leopard seal and six from Weddell seals.
乳头瘤病毒（家族乳头瘤病毒科）是无包膜的圆形双链 DNA 病毒，已知可感染鳞状和黏膜上皮细胞。在乳头瘤病毒科中，有 53 个属和 133 种病毒，其成员感染了多种哺乳动物、鸟类、爬行动物和鱼类。在南极环境中，已在阿德利企鹅（Pygoscelis adeliae，2 种乳头瘤病毒）、威德尔海豹（Leptonychotes weddellii，7 种乳头瘤病毒）和南极绿鳕鱼（Trematomus bernacchii，1 种乳头瘤病毒）中鉴定出乳头瘤病毒（PVs）在麦克默多海峡和罗斯岛的东部南极洲。在这里，我们从西部南极洲（南极半岛）的南极软毛海豹（Arctocephalus gazella，2 种乳头瘤病毒）和豹形海豹（Hydrurga leptonyx，3 种乳头瘤病毒）的口腔拭子中以及麦克默多海峡的威德尔海豹（8 种乳头瘤病毒）的阴道和鼻腔拭子中鉴定出 13 种不同的 PVs。这些 PV 基因组分为四个属，代表 11 种新的乳头瘤病毒类型，其中 5 种来自两种南极软毛海豹和一种豹形海豹，6 种来自威德尔海豹。
