Varsani Arvind, Frankfurter Greg, Stainton Daisy, Male Maketalena F, Kraberger Simona, Burns Jennifer M
The Biodesign Center for Fundamental and Applied Microbiomics, Center for Evolution and Medicine, School of Life Sciences, Arizona State University, Tempe, AZ, 85287-5001, USA.
School of Biological Sciences, University of Canterbury, Christchurch, 8140, New Zealand.
Arch Virol. 2017 May;162(5):1403-1407. doi: 10.1007/s00705-017-3239-y. Epub 2017 Jan 25.
Viruses are ubiquitous in nature, however, very few have been identified that are associated with Antarctic animals. Here we report the identification of a polyomavirus in the kidney tissue of a deceased Weddell seal from the Ross Sea, Antarctica. The circular genome (5186 nt) has typical features of polyomaviruses with a small and larger T-antigen open reading frames (ORFs) and three ORFs encoding VP1, VP2 and VP3 capsid proteins. The genome of the Weddell seal polyomavirus (WsPyV) shares 85.4% genome-wide pairwise identity with a polyomavirus identified in a California sea lion. To our knowledge WsPyV is the first viral genome identified in Antarctic pinnipeds and the third polyomavirus to be identified from an Antarctic animal, the other two being from Adélie penguin (Pygoscelis adeliae) and a sharp-spined notothen (Trematomus pennellii), both sampled in the Ross sea. The GenBank accession number: KX533457.
病毒在自然界中无处不在，然而，已确定与南极动物相关的病毒却非常少。在此，我们报告在一只来自南极罗斯海的死亡威德尔海豹的肾脏组织中鉴定出一种多瘤病毒。该环状基因组（5186个核苷酸）具有多瘤病毒的典型特征，包含一个小的和一个大的T抗原开放阅读框（ORF）以及三个编码衣壳蛋白VP1、VP2和VP3的ORF。威德尔海豹多瘤病毒（WsPyV）的基因组与在加利福尼亚海狮中鉴定出的一种多瘤病毒在全基因组水平上具有85.4%的成对同一性。据我们所知，WsPyV是在南极鳍足类动物中鉴定出的首个病毒基因组，也是从南极动物中鉴定出的第三种多瘤病毒，另外两种分别来自阿德利企鹅（阿德利企鹅属）和一种尖棘南极鱼（彭氏南极鱼），均采自罗斯海。GenBank登录号：KX533457。
