Alkharashi Majed, Otaif Wael
Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia; Department of Ophthalmology, King Khalid University Medical City, Abha, Saudi Arabia.
Int J Surg Case Rep. 2024 Apr;117:109491. doi: 10.1016/j.ijscr.2024.109491. Epub 2024 Mar 15.
Descemet membrane endothelial keratoplasty (DMEK) is commonly used to treat endothelial pathologies in bicameral pseudophakic eyes with a normal depth of the anterior chamber. However, performing this procedure on eyes that have undergone vitrectomy carries a higher risk of complications. Therefore, this report presents a novel technique for improving the unfolding of a DMEK graft in a vitrectomized eye.
A 49-year-old man with a history of complicated cataract surgery one year prior was referred to our clinic with pseudophakic bullous keratopathy in his left eye. The surgery involved a posterior capsular rupture, anterior vitrectomy, and implantation of a sulcus three-piece intraocular lens. DMEK and anterior vitrectomy were performed. However, the conventional tap technique was unsuccessful in unfolding the DMEK graft, owing to intraoperative hypotony and an inability to flatten the anterior chamber.
To minimize excessive manipulation of the donor tissue, a 27-gauge cannula attached to a 3-cc syringe was used. A cannula was introduced through paracentesis near the edge of an unfolded DMEK graft. We then created a suction force by pulling back the plunger while slowly moving the needle backward during the graft unfolding. The postoperative course was uneventful, with a clear and fully attached DMEK graft.
This technique reduces the complexity of DMEK graft unfolding in vitrectomized eyes, enabling easier and more controlled unfolding. However, further research with larger patient populations is required to determine the clinical relevance of this method.
Descemet膜内皮角膜移植术(DMEK)常用于治疗前房深度正常的双腔人工晶状体眼的内皮病变。然而,在接受过玻璃体切除术的眼睛上进行该手术会带来更高的并发症风险。因此,本报告介绍了一种在玻璃体切除术后的眼睛中改善DMEK移植物展开的新技术。
一名49岁男性,一年前有复杂白内障手术史,因左眼人工晶状体性大泡性角膜病变转诊至我院。手术包括后囊破裂、前部玻璃体切除术和植入沟内三片式人工晶状体。进行了DMEK和前部玻璃体切除术。然而,由于术中低眼压和无法使前房变平,传统的穿刺技术未能成功展开DMEK移植物。
为尽量减少对供体组织的过度操作,使用了连接到3毫升注射器的27号套管针。通过在展开的DMEK移植物边缘附近的穿刺口插入套管针。然后在移植物展开过程中,通过向后拉动活塞并缓慢向后移动针头来产生吸力。术后过程顺利,DMEK移植物清晰且完全附着。
该技术降低了玻璃体切除术后眼睛中DMEK移植物展开的复杂性,使展开更容易且更可控。然而,需要对更大的患者群体进行进一步研究以确定该方法的临床相关性。