Yoshino Ryusei, Nakatsubo Masaki, Ujiie Nanami, Kitada Masahiro
Thoracic Surgery and Breast Surgery, Asahikawa Medical University Hospital, Asahikawa, JPN.
Cureus. 2024 Feb 21;16(2):e54641. doi: 10.7759/cureus.54641. eCollection 2024 Feb.
Wilson-Mikity syndrome (WMS) is a rare condition characterized by various respiratory and pulmonary abnormalities in neonates and infants. However, the diagnosis is based on the findings of physiological tests, such as respiratory function tests. Reports describing the histopathological features of WMS are limited. The patient was a 22-year-old woman with a history of WMS. She had been on a ventilator for the first three months of life due to pulmonary hypertension after early delivery at 24 weeks of gestation and required oxygen therapy until three years of age. One month before presenting at our clinic, the patient experienced chest pain and respiratory distress, and a left spontaneous pneumothorax was diagnosed based on a chest X-ray examination. The pneumothorax improved after the insertion of a thoracic drain but recurred soon thereafter. A histopathological examination revealed emphysematous changes associated with WMS in the background lungs, consistent with brevity. No postoperative complications were observed. The thoracic drain was removed on the second day, and the patient was discharged on the eighth postoperative day. Postoperatively, the patient was started on inhaled medication and was carefully monitored every three months. The present case suggests that childhood interviews are very important for adult patients who develop pneumothorax and that early surgical treatment may be selected based on a detailed interview. Moreover, postoperative follow-up should be carefully performed in collaboration with respiratory medicine in patients with pneumothorax originating from chronic obstructive pulmonary diseases such as WMS.
威尔逊-米基蒂综合征(WMS)是一种罕见病症,其特征为新生儿和婴儿出现各种呼吸及肺部异常。然而,诊断基于生理测试结果,如呼吸功能测试。描述WMS组织病理学特征的报告有限。该患者为一名22岁女性,有WMS病史。她在妊娠24周早产出生后,因肺动脉高压在出生后的头三个月使用呼吸机,并且在三岁前一直需要吸氧治疗。在到我们诊所就诊前一个月,患者出现胸痛和呼吸窘迫,胸部X线检查诊断为左侧自发性气胸。胸腔引流管置入后气胸有所改善,但随后很快复发。组织病理学检查显示,背景肺组织存在与WMS相关的肺气肿改变,与简述一致。未观察到术后并发症。术后第二天拔除胸腔引流管,患者在术后第八天出院。术后,患者开始吸入药物治疗,并每三个月接受仔细监测。本病例表明,对于发生气胸的成年患者,儿童时期的问诊非常重要,并且可以根据详细问诊选择早期手术治疗。此外,对于源自慢性阻塞性肺疾病如WMS的气胸患者,术后应与呼吸内科合作仔细进行随访。