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双侧视神经周围炎合并特发性颅内高压病例报告:诊断与治疗挑战

A Case Report of Bilateral Optic Perineuritis With Idiopathic Intracranial Hypertension: Challenges in Diagnosis and Management.

作者信息

Shahrudin Nurul-Farah H, Muhammed Julieana, Wan Hitam Wan-Hazabbah, Sapiai Nur Asma, Abdul Halim Sanihah

机构信息

Department of Ophthalmology and Visual Science, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, MYS.

Department of Radiology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, MYS.

出版信息

Cureus. 2024 Feb 22;16(2):e54692. doi: 10.7759/cureus.54692. eCollection 2024 Feb.

DOI:10.7759/cureus.54692
PMID:38523970
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10960579/
Abstract

Optic perineuritis (OPN) refers to the inflammation of the optic nerve sheath and it is a rare form of idiopathic orbital inflammatory disease. We report a rare case of bilateral OPN in an obese female teenager with idiopathic intracranial hypertension (IIH). She was initially presented with painless bilateral blurring of vision that was progressively worsening for three weeks duration. Visual acuity of both eyes was hand movement with no relative afferent pupillary defect detected. The confrontation visual field test showed central scotoma. Both anterior segments were unremarkable. Fundoscopy showed a swollen optic disc bilaterally, with extensive flame-shaped hemorrhages surrounding the disc area and dot blot hemorrhages in the posterior pole. A magnetic resonance imaging scan of the brain and orbit revealed the presence of bilateral optic nerve sheath enhancement with empty sella turcica. The patient was diagnosed with bilateral OPN with IIH. She received an initial high dose of systemic corticosteroid followed by a slow tapering dose. She was monitored by the neuromedical team for her IIH. She was followed up for about a year. The final best corrected visual acuity in the right eye was 6/36 and the left eye was 6/60. In conclusion, OPN poses challenges in diagnosis and management. This case emphasizes the importance of considering OPN in the differential diagnosis of optic nerve-related symptoms, as prompt recognition and intervention are crucial for favorable outcomes.

摘要

视神经周围炎(OPN)是指视神经鞘的炎症,是一种罕见的特发性眼眶炎性疾病。我们报告了一例肥胖女性青少年双侧OPN合并特发性颅内高压(IIH)的罕见病例。她最初表现为双侧无痛性视力模糊,持续三周且逐渐加重。双眼视力为手动,未检测到相对传入性瞳孔障碍。对侧视野检查显示中心暗点。眼前节均无异常。眼底镜检查显示双侧视盘肿胀,视盘周围有广泛的火焰状出血,后极部有点状和斑状出血。脑部和眼眶的磁共振成像扫描显示双侧视神经鞘强化,伴有空蝶鞍。该患者被诊断为双侧OPN合并IIH。她最初接受了高剂量的全身性皮质类固醇治疗,随后逐渐减量。神经医学团队对她的IIH进行监测。她接受了约一年的随访。右眼最终最佳矫正视力为6/36,左眼为6/60。总之,OPN在诊断和治疗方面存在挑战。该病例强调了在视神经相关症状的鉴别诊断中考虑OPN的重要性,因为及时识别和干预对于取得良好预后至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cf6/10960579/92623021e1d7/cureus-0016-00000054692-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cf6/10960579/0b194bff8b25/cureus-0016-00000054692-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cf6/10960579/a1217f1f80f8/cureus-0016-00000054692-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cf6/10960579/0983a7e9262b/cureus-0016-00000054692-i03.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cf6/10960579/d6136879e6ce/cureus-0016-00000054692-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cf6/10960579/126e781e43bf/cureus-0016-00000054692-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cf6/10960579/92623021e1d7/cureus-0016-00000054692-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cf6/10960579/0b194bff8b25/cureus-0016-00000054692-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cf6/10960579/a1217f1f80f8/cureus-0016-00000054692-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cf6/10960579/0983a7e9262b/cureus-0016-00000054692-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cf6/10960579/aed5554b7cbd/cureus-0016-00000054692-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cf6/10960579/d6136879e6ce/cureus-0016-00000054692-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cf6/10960579/126e781e43bf/cureus-0016-00000054692-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cf6/10960579/92623021e1d7/cureus-0016-00000054692-i07.jpg

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本文引用的文献

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The diagnostic dilemma of bilateral optic neuritis and idiopathic intracranial hypertension coexistence in a patient with recent COVID-19 infection.一名近期感染新冠病毒的患者出现双侧视神经炎和特发性颅内高压并存的诊断困境。
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