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低剂量阿司匹林对老年人的影响。

Effect of Low-Dose Aspirin on the Elderly.

作者信息

Darraj Ali

机构信息

Department of Medicine, College of Medicine, Shaqra University, Shaqra, SAU.

出版信息

Cureus. 2024 Feb 21;16(2):e54658. doi: 10.7759/cureus.54658. eCollection 2024 Feb.

Abstract

Aspirin is a recognized and affordable antiplatelet medicine. Low amounts of aspirin have been used to prevent cardiovascular events, and it is still widely used for primary and secondary stroke prevention. The purpose of this review article is to evaluate the effects of using low doses of aspirin among elderly people. Although taking large dosages of aspirin (500 mg daily) reduces the long-term risk of colorectal cancer, its effectiveness for long-term prevention may be limited by adverse effects. Studies have assessed the relationship between aspirin dosage, incidence, and death in patients with colorectal cancer. Research has indicated that those with diabetes mellitus have an increased risk of cardiovascular events. Low amounts of aspirin have been used to prevent cardiovascular events. However, there is uncertainty regarding the potential benefits and risks associated with preventing the development of cardiovascular problems in individuals with diabetes. The use of aspirin lowers the risk of occlusive vascular events but raises the possibility of bleeding. More attention should be paid to reducing inappropriate aspirin usage in light of its prevalence, particularly among older persons, as the substantial continuous usage of this drug increases the chances of bleeding.

摘要

阿司匹林是一种公认且价格亲民的抗血小板药物。小剂量阿司匹林已被用于预防心血管事件,并且仍广泛用于一级和二级卒中预防。这篇综述文章的目的是评估在老年人中使用低剂量阿司匹林的效果。尽管服用大剂量阿司匹林(每日500毫克)可降低结直肠癌的长期风险,但其长期预防效果可能会受到不良反应的限制。研究已经评估了阿司匹林剂量、结直肠癌患者的发病率和死亡率之间的关系。研究表明,糖尿病患者发生心血管事件的风险增加。小剂量阿司匹林已被用于预防心血管事件。然而,对于预防糖尿病患者发生心血管问题的潜在益处和风险尚不确定。使用阿司匹林可降低闭塞性血管事件的风险,但会增加出血的可能性。鉴于其普遍性,尤其是在老年人中,应更加关注减少阿司匹林的不适当使用,因为持续大量使用这种药物会增加出血几率。

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Effect of Low-Dose Aspirin on the Elderly.低剂量阿司匹林对老年人的影响。
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10. Cardiovascular Disease and Risk Management: .10. 心血管疾病与风险管理: 。
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