Elanjian Alissa I, Law Jason P, Hrinczenko Borys
Medical Education, Michigan State University College of Human Medicine, East Lansing, USA.
Internal Medicine, Michigan State University College of Human Medicine, East Lansing, USA.
Cureus. 2024 Feb 22;16(2):e54689. doi: 10.7759/cureus.54689. eCollection 2024 Feb.
(MG) is one of the least pathogenic nontuberculous mycobacteria (NTM). We report an unusual case of MG infection in a patient with newly diagnosed lung cancer. A 61-year-old woman presented with shortness of breath and weight loss. Six months prior to admission, she was diagnosed with MG infection based on positive sputum cultures and bronchioalveolar lavage. Despite anti-mycobacterial therapy, her symptoms worsened and she lost approximately 100 pounds. A transbronchial biopsy obtained one week prior to admission revealed adenocarcinoma of the lung. At admission, vital signs were normal, and a physical exam revealed bilateral crackles. Computed tomography (CT) scan of the chest revealed infiltrates with ground-glass opacity. The patient was admitted to the oncology service for evaluation. Our findings suggest that symptomatic individuals with positive cultures of MG should proceed with extensive workup for possible underlying lung cancer especially if not responding to anti-mycobacterial therapy.
鸟型分枝杆菌（MG）是致病性最低的非结核分枝杆菌（NTM）之一。我们报告了一例新诊断为肺癌的患者发生MG感染的罕见病例。一名61岁女性出现呼吸急促和体重减轻症状。入院前6个月，根据痰培养和支气管肺泡灌洗结果呈阳性，她被诊断为MG感染。尽管接受了抗分枝杆菌治疗，她的症状仍恶化，体重减轻了约100磅。入院前一周进行的经支气管活检显示为肺腺癌。入院时，生命体征正常，体格检查发现双侧有啰音。胸部计算机断层扫描（CT）显示有磨玻璃样渗出影。患者被收入肿瘤科进行评估。我们的研究结果表明，MG培养阳性的有症状个体应进行全面检查，以排查可能存在的潜在肺癌，尤其是在对抗分枝杆菌治疗无反应的情况下。
