Bassi Shikha Talwar, Salim Shebin, Rishi Ekta
Department of Neuroophthalmology Services, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Department of Comprehensive Ophthalmology Services, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Oman J Ophthalmol. 2024 Feb 21;17(1):53-58. doi: 10.4103/ojo.ojo_75_23. eCollection 2024 Jan-Apr.
The purpose of this study was to evaluate the outcomes of phacoemulsification with intravitreal triamcinolone acetonide (IVTA) injection in patients with cataract and diabetic macular edema (DME) across the grades of diabetic retinopathy (DR).
It was a retrospective observational study. The study included 70 patients (75 eyes) with cataract and clinically significant macular edema in diabetics with nonproliferative (61 eyes) or proliferative (14 eyes) DR who underwent phacoemulsification with IVTA. Visual outcome and progression of DME over 3 months were studied in terms of the best-corrected visual acuity (BCVA) and central macular thickness (CMT), respectively.
The case records of 70 patients (75 eyes) were studied. The mean baseline BCVA ( = 75) in the logMAR scale ± SD was 0.92 ± 0.53. 3 weeks after the surgery, the mean BCVA improved to 0.39 ± 0.26 and the mean CMT ( = 40) was 382.57 ± 192.30 compared with the mean preoperative CMT of 480.57 ± 163.25 in the same set ( = 0.01). The mean CMT decreased at 3 weeks in 22 (55% of the eyes). An improvement of ≥2 lines was seen at 3 weeks in 52 (69.33%) eyes and in 49 (65.33%) eyes at 3 months. The mean CMT at 3 months was 445.51 ± 222.99 ( = 70) compared to the preoperative mean CMT of 470.72 ± 176.15 in the same set ( = 0.29). The mean CMT decreased at 3 months in 34 (48.5%) eyes.
Phacoemulsification with IVTA injection improved the mean visual acuity at 3 weeks and 3 months in two-thirds of cases and decreased the mean CMT at 3 weeks in nearly half the numbers.
本研究旨在评估白内障合并糖尿病性黄斑水肿（DME）患者在不同程度糖尿病视网膜病变（DR）情况下，行超声乳化白内障吸除术联合玻璃体内注射曲安奈德（IVTA）的治疗效果。
这是一项回顾性观察研究。该研究纳入了70例（75只眼）患有白内障且伴有临床上显著黄斑水肿的糖尿病患者，这些患者患有非增殖性（61只眼）或增殖性（14只眼）DR，均接受了超声乳化白内障吸除术联合IVTA治疗。分别根据最佳矫正视力（BCVA）和中心黄斑厚度（CMT）研究了3个月内DME的视力结果和进展情况。
研究了70例患者（75只眼）的病例记录。以logMAR量表表示的平均基线BCVA（n = 75）±标准差为0.92±0.53。术后3周，平均BCVA提高到0.39±0.26，与同一组术前平均CMT 480.57±163.25相比，平均CMT（n = 40）为382.57±192.30（P = 0.01）。22只眼（占55%）在3周时平均CMT下降。52只眼（69.33%）在3周时视力提高≥2行，49只眼（65.33%）在3个月时视力提高≥2行。与同一组术前平均CMT 470.72±176.15相比，3个月时平均CMT为445.51±222.99（n = 70）（P = 0.29）。34只眼（48.5%）在3个月时平均CMT下降。
超声乳化白内障吸除术联合IVTA注射在三分之二的病例中提高了3周和3个月时的平均视力，近半数患者在3周时平均CMT下降。
