Prakash Aishwarya, Basappa Suma, Jeebula Bhavya, Nagaraju Doddahalli H, Dhayal Rajendra S, Bose Shubhankar Kumar
Centre for Nano and Material Sciences (CNMS), Jain University, Jain Global Campus, Bangalore 562112, India.
Department of Chemistry, School of Applied Sciences, REVA University, Bangalore 560064, India.
Org Lett. 2024 Apr 5;26(13):2569-2573. doi: 10.1021/acs.orglett.4c00535. Epub 2024 Mar 25.
We report a recyclable and efficient catalyst system based on a nickel-benzene tricarboxylic acid metal-organic framework (Ni-BTC MOF) for the borylation of aryl halides, including aryl chlorides, with (pinacolato)diboron, affording aryl boronate esters in high yields (up to >99% yield) with high selectivity. This protocol demonstrates broad functional group tolerance. Catalyst can be recyclable up to four times, and gram-scale reactions further highlights the usefulness of this method. EPR experiments confirmed the formation of catalytically active Ni(I) species.
我们报道了一种基于镍-苯三甲酸金属有机框架（Ni-BTC MOF）的可回收且高效的催化剂体系，用于芳基卤化物（包括芳基氯化物）与（频哪醇）二硼的硼化反应，能以高收率（高达>99%收率）和高选择性得到芳基硼酸酯。该方法显示出广泛的官能团耐受性。催化剂可回收使用多达四次，克级规模的反应进一步突出了该方法的实用性。电子顺磁共振实验证实了催化活性Ni(I)物种的形成。
