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探索氟喹诺酮类抗生素的环境途径和挑战:最新综述。

Exploring the environmental pathways and challenges of fluoroquinolone antibiotics: A state-of-the-art review.

机构信息

School of Architecture, Civil, Environmental and Energy Engineering, Kyungpook National University, Daegu 41566, Republic of Korea.

Research Center for Environmental and Clean Technology, National Research and Innovation Agency, Badan Riset dan Inovasi Nasional, BRIN, Serpong 15314, Indonesia.

出版信息

Sci Total Environ. 2024 May 20;926:171944. doi: 10.1016/j.scitotenv.2024.171944. Epub 2024 Mar 26.

Abstract

Fluoroquinolone (FQ) antibiotics have become a subject of growing concern due to their increasing presence in the environment, particularly in the soil and groundwater. This review provides a comprehensive examination of the attributes, prevalence, ecotoxicity, and remediation approaches associated with FQs in environmental matrices. The paper discusses the physicochemical properties that influence the fate and transport of FQs in soil and groundwater, exploring the factors contributing to their prevalence in these environments. Furthermore, the ecotoxicological implications of FQ contamination in soil and aquatic ecosystems are reviewed, shedding light on the potential risks to environmental and human health. The latter part of the review is dedicated to an extensive analysis of remediation approaches, encompassing both in-situ and ex-situ methods employed to mitigate FQ contamination. The critical evaluation of these remediation strategies provides insights into their efficacy, limitations, and environmental implications. In this investigation, a correlation between FQ antibiotics and climate change is established, underlining its significance in addressing the Sustainable Development Goals (SDGs). The study further identifies and delineates multiple research gaps, proposing them as key areas for future investigational directions. Overall, this review aims to consolidate current knowledge on FQs in soil and groundwater, offering a valuable resource for researchers, policymakers, and practitioners engaged in environmental management and public health.

摘要

氟喹诺酮(FQ)抗生素由于其在环境中(尤其是土壤和地下水中)的存在日益增加,已成为人们越来越关注的问题。本综述全面考察了 FQ 在环境基质中的属性、普遍性、生态毒性以及修复方法。本文讨论了影响 FQ 在土壤和地下水中的归趋和迁移的物理化学性质,探讨了导致其在这些环境中普遍存在的因素。此外,还审查了 FQ 污染对土壤和水生生态系统的生态毒性影响,阐明了其对环境和人类健康的潜在风险。本综述的后半部分专门分析了修复方法,包括用于减轻 FQ 污染的原位和异位方法。对这些修复策略的批判性评估提供了对其有效性、局限性和环境影响的深入了解。在本研究中,确立了 FQ 抗生素与气候变化之间的相关性,强调了在实现可持续发展目标(SDGs)方面解决这一问题的重要性。本研究还确定并描述了多个研究空白,将其作为未来研究方向的重点领域。总的来说,本综述旨在整合关于土壤和地下水中 FQ 的现有知识,为从事环境管理和公共卫生的研究人员、政策制定者和从业者提供有价值的资源。

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