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多中心儿科和先天性心血管磁共振研究的设计与实施:小身体中的大数据。

Design and implementation of multicenter pediatric and congenital studies with cardiovascular magnetic resonance: Big data in smaller bodies.

机构信息

Division of Cardiology, Department of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian Morgan Stanley Children's Hospital, 3959 Broadway, New York, NY 10032, USA.

Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.

出版信息

J Cardiovasc Magn Reson. 2024 Summer;26(1):101041. doi: 10.1016/j.jocmr.2024.101041. Epub 2024 Mar 23.

DOI:10.1016/j.jocmr.2024.101041
PMID:38527706
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10990896/
Abstract

Cardiovascular magnetic resonance (CMR) has become the reference standard for quantitative and qualitative assessment of ventricular function, blood flow, and myocardial tissue characterization. There is a preponderance of large CMR studies and registries in adults; However, similarly powered studies are lacking for the pediatric and congenital heart disease (PCHD) population. To date, most CMR studies in children are limited to small single or multicenter studies, thereby limiting the conclusions that can be drawn. Within the PCHD CMR community, a collaborative effort has been successfully employed to recognize knowledge gaps with the aim to embolden the development and initiation of high-quality, large-scale multicenter research. In this publication, we highlight the underlying challenges and provide a practical guide toward the development of larger, multicenter initiatives focusing on PCHD populations, which can serve as a model for future multicenter efforts.

摘要

心血管磁共振(CMR)已成为定量和定性评估心室功能、血流和心肌组织特征的参考标准。成人中有大量的 CMR 研究和注册,但在儿科和先天性心脏病(PCHD)人群中,同样规模的研究则缺乏。迄今为止,大多数儿童 CMR 研究仅限于小型的单中心或多中心研究,从而限制了可以得出的结论。在 PCHD CMR 社区内,已经成功地采用了合作努力来认识知识空白,旨在鼓励开展高质量、大规模的多中心研究。在本出版物中,我们强调了潜在的挑战,并提供了一个实用指南,帮助制定专注于 PCHD 人群的更大规模的多中心计划,这可以作为未来多中心努力的模式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccb5/10990896/25a0ff646334/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccb5/10990896/13abbc54c46a/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccb5/10990896/e66b0a186b5e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccb5/10990896/cb3a5ecee34d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccb5/10990896/25a0ff646334/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccb5/10990896/13abbc54c46a/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccb5/10990896/e66b0a186b5e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccb5/10990896/cb3a5ecee34d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccb5/10990896/25a0ff646334/gr3.jpg

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