局部交替冷热刺激对疲劳肌肉组织的血液动力学和氧合及自主神经活动的影响：一项单臂干预研究。

Local alternating heat and cold stimulation affects hemodynamics and oxygenation in fatigued muscle tissue and autonomic nervous activity: a single-arm interventional study.

机构信息

Diagnosis and Treatment Division, Nagura Orthopedic Clinic, Chuo, Tokyo, Japan.

Department of Orthopaedic Surgery, Keio University School of Medicine, Shinjuku, Tokyo, Japan.

出版信息

J Physiol Anthropol. 2024 Mar 25;43(1):11. doi: 10.1186/s40101-024-00358-3.

DOI:10.1186/s40101-024-00358-3

PMID:38528599

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10964554/

Abstract

BACKGROUND

Local alternating heat and cold stimulation as an alternative to contrast bath may cause intermittent vasoconstriction and vasodilation, inducing a vascular pumping effect and consequently promoting increased tissue blood flow and oxygenation. This study aimed to examine the effects of local alternating heat and cold stimulation, using a wearable thermal device, on the hemodynamics of fatigued muscle tissue and autonomic nervous activity.

METHODS

Twenty healthy individuals experienced fatigue in the periarticular muscles of the shoulder joint due to a typing task. Local alternating heat and cold stimulations were then applied to the upper trapezius muscle. Muscle hardness was measured using a muscle hardness meter, and muscle tissue hemodynamics and oxygenation were evaluated using near-infrared spectroscopy before and after the stimulation. Autonomic nervous activity was also evaluated using heart rate variability.

RESULTS

Alternating heat and cold stimulation decreased muscle hardness of the fatigued trapezius muscle from 1.38 ± 0.15 to 1.31 ± 0.14 N (P < 0.01). The concentration of total hemoglobin in the trapezius muscle tissue increased from - 0.21 ± 1.36 to 2.29 ± 3.42 µmol/l (P < 0.01), and the tissue hemoglobin oxygen saturation also increased from 70.1 ± 5.4 to 71.1 ± 6.0% (P < 0.05). Additionally, the heart rate variability parameter, which is an index of sympathetic nervous activity, increased from 3.82 ± 2.96 to 6.86 ± 3.49 (P < 0.01). A correlation was found between increased tissue hemoglobin oxygen saturation and increased parameters of sympathetic nervous activity (r = 0.50, P < 0.05).

CONCLUSIONS

Local alternating heat and cold stimulation affected the hemodynamic response in fatigued muscle tissue and autonomic nervous activity. This stimulation is more efficient than conventional contrast baths in terms of mobility and temperature control and has potential as a new versatile therapeutic intervention for muscle fatigue.

TRIAL REGISTRATION

UMIN-CTR (UMIN000040087: registered on April 7, 2020, https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000045710 . UMIN000040620: registered on June 1, 2020, https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000046359 ).

摘要

背景

局部交替冷热刺激作为对比浴的替代方法，可能会引起间歇性的血管收缩和扩张，从而产生血管泵送效应，进而促进组织血液流量和氧合增加。本研究旨在使用可穿戴式热设备检查局部交替冷热刺激对疲劳肌肉组织的血液动力学和自主神经活动的影响。

方法

20 名健康个体由于肩部关节的打字任务而导致关节周围肌肉疲劳。然后将局部交替的冷热刺激应用于上斜方肌。使用肌肉硬度计测量肌肉硬度，在刺激前后使用近红外光谱仪评估肌肉组织血液动力学和氧合。还使用心率变异性评估自主神经活动。

结果

交替的冷热刺激使疲劳的斜方肌肌肉硬度从 1.38±0.15 降至 1.31±0.14 N（P<0.01）。斜方肌组织中总血红蛋白的浓度从-0.21±1.36 增加到 2.29±3.42 μmol/L（P<0.01），组织血红蛋白氧饱和度也从 70.1±5.4 增加到 71.1±6.0%（P<0.05）。此外，作为交感神经活动指标的心率变异性参数从 3.82±2.96 增加到 6.86±3.49（P<0.01）。组织血红蛋白氧饱和度增加与交感神经活动参数增加之间存在相关性（r=0.50，P<0.05）。