Department of Respiratory Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Thorac Cancer. 2024 May;15(13):1106-1111. doi: 10.1111/1759-7714.15270. Epub 2024 Mar 25.
Tracheomediastinal fistula is a rare but life-threatening complication of cancer. We report a case of tracheomediastinal fistula induced by concurrent chemoradiotherapy in limited stage small cell lung cancer. Despite the treatment response, the metastatic paratracheal lymph node increased gradually during concurrent chemoradiotherapy, resulting in the occurrence of tracheomediastinal fistula and mediastinitis. Without any surgical intervention, the patient achieved successful recovery from mediastinitis through antibiotic treatment, although the tracheomediastinal fistula remained open. In this report, we also review previous studies of tracheomediastinal and bronchomediastinal fistulas and summarize the clinical features.
气管-纵隔瘘是癌症的一种罕见但危及生命的并发症。我们报告了一例局限期小细胞肺癌同步放化疗引起的气管-纵隔瘘。尽管治疗反应良好，但在同步放化疗过程中转移性气管旁淋巴结逐渐增大，导致气管-纵隔瘘和纵隔炎的发生。在没有任何手术干预的情况下，患者通过抗生素治疗成功治愈了纵隔炎，尽管气管-纵隔瘘仍然存在。在本报告中，我们还回顾了既往气管-纵隔瘘和支气管-纵隔瘘的研究，并总结了其临床特征。
