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与中心血液透析相比,新型家庭透析技术的成本是否仍然具有优势?一项意大利单中心分析及与西方国家经验的比较。

Is the cost of the new home dialysis techniques still advantageous compared to in-center hemodialysis? An Italian single center analysis and comparison with experiences from western countries.

作者信息

Iadarola Gian Maria, Giorda Elisa, Borca Marco, Morero Daniela, Sciascia Savino, Roccatello Dario

机构信息

University Center of Excellence on Nephrological, Rheumatological and Rare Diseases (ERK-net, ERN-Reconnect and RITA-ERN Member) Including Nephrology and Dialysis Unit and Center of Immuno-Rheumatology and Rare Diseases (CMID), Coordinating Center of the Interregional Network for Rare Diseases of Piedmont and Aosta Valley (North-West Italy), San Giovanni Bosco Hub Hospital, ASL Città di Torino and Department of Clinical and Biological Sciences of the University of Turin, Turin, Italy.

出版信息

Front Med (Lausanne). 2024 Mar 11;11:1345506. doi: 10.3389/fmed.2024.1345506. eCollection 2024.

Abstract

INTRODUCTION

Potential advantages of home dialysis remained a questionable issue. Three main factors have to be considered: the progressive reduction in the cost of consumables for in-Center hemodialysis (IC-HD), the widespread use of incremental Peritoneal Dialysis (PD), and the renewed interest in home hemodialysis (H-HD) in the pandemic era. Registries data on prevalence of dialysis modalities generally report widespread underemployment of home dialysis despite PD and H-HD could potentially provide clinical benefits, improve quality of life, and contrast the diffusion of new infection among immunocompromised patients.

METHODS

We examined the economic impact of home dialysis by comparing the direct and indirect costs of PD (53 patients), H-HD (21 patients) and IC-HD (180 patients) in a single hospital of North-west Italy. In order to achieve comparable weekly costs, the average weekly frequency of dialysis sessions based on the dialysis modality was calculated, the cost of individual sessions per patient per week normalized, and the monthly and yearly costs were derived.

RESULTS

As expected, PD resulted the least expensive procedure (€ 23,314.79 per patient per year), but, notably, H-HD has a lower average cost than IC-HD (€ 35,535.00 vs. € 40,798.98). A cost analysis of the different dialysis procedures confirms the lower cost of PD, especially continuous ambulatory PD, compared to any extracorporeal technique.

DISCUSSION

Among the hemodialysis techniques, home bicarbonate HD showed the lowest costs, while the weekly cost of Frequent Home Hemodialysis was found to be comparable to In-Center Bicarbonate Hemodialysis.

摘要

引言

家庭透析的潜在优势仍是一个有争议的问题。需要考虑三个主要因素:中心血液透析(IC-HD)耗材成本的逐步降低、间歇性腹膜透析(PD)的广泛使用以及大流行时代对家庭血液透析(H-HD)重新产生的兴趣。尽管腹膜透析和家庭血液透析可能会带来临床益处、改善生活质量并减少免疫功能低下患者中新感染的传播,但透析方式患病率的登记数据通常显示家庭透析的利用率普遍较低。

方法

我们通过比较意大利西北部一家医院中腹膜透析(53例患者)、家庭血液透析(21例患者)和中心血液透析(180例患者)的直接和间接成本,研究了家庭透析的经济影响。为了实现可比的每周成本,根据透析方式计算了透析疗程的平均每周频率,对每位患者每周每次疗程的成本进行了标准化,并得出了每月和每年的成本。

结果

正如预期的那样,腹膜透析是成本最低的治疗方法(每位患者每年23,314.79欧元),但值得注意的是,家庭血液透析的平均成本低于中心血液透析(35,535.00欧元对40,798.98欧元)。对不同透析程序的成本分析证实,与任何体外技术相比,腹膜透析成本更低,尤其是持续非卧床腹膜透析。

讨论

在血液透析技术中,家庭碳酸氢盐血液透析成本最低,而频繁家庭血液透析的每周成本与中心碳酸氢盐血液透析相当。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e6b/10961330/4e51b6836124/fmed-11-1345506-g001.jpg

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