预测青少年到成年早期 BMI 变化的神经认知因素。

Neurocognitive factors predicting BMI changes from adolescence to young adulthood.

机构信息

Laboratory of Sleep and Functional Neurobiology, Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile.

Academic General Pediatrics, Child Development, and Community Health, University of California, San Diego, San Diego, California, USA.

出版信息

Obesity (Silver Spring). 2024 Apr;32(4):768-777. doi: 10.1002/oby.23978.

DOI:10.1002/oby.23978

PMID:38529547

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10965240/

Abstract

OBJECTIVE

The objective of this study was to assess whether inhibitory task performance in adolescence could be prospectively related to weight gain in young adulthood. We proposed that this association would differ according to the BMI group in adolescence.

METHODS

A total of 318 adolescents performed the anti-saccade task, and 530 completed the Stroop test. Accuracy and reaction time were assessed for each incentive type (neutral, loss, and reward) in the anti-saccade task and for each trial type (control and incongruent trials) in the Stroop test. Changes in the BMI z score (∆BMI z score) from adolescence to young adulthood were calculated.

RESULTS

The relationship between the BMI z score and the anti-saccade task accuracy showed an effect on the ∆BMI z score (β = -0.002, p < 0.05). The neutral and loss accuracies were related to ∆BMI z score in the groups with overweight (all β = -0.004, p = 0.05) and obesity (β = -0.006 and β = -0.005, p < 0.01). The interaction between adolescents' BMI z score with control (β = -0.312, p < 0.001) and incongruent (β = -0.384, p < 0.001) trial reaction times showed an effect on the ∆BMI z score. Control (β = 0.730, p = 0.036) and incongruent (β = 0.535, p = 0.033) trial reaction times were related to ∆BMI z score in the group with overweight.

CONCLUSIONS

Our findings support the hypothesis that cognitive vulnerability could predict the BMI gain from adolescence to young adulthood.

摘要

目的

本研究旨在评估青少年时期的抑制任务表现是否与青年期体重增加有前瞻性关系。我们假设这种关联会根据青少年时期的 BMI 组别而有所不同。

方法

共有 318 名青少年完成了反眼跳任务，530 名青少年完成了 Stroop 测试。反眼跳任务中，对每种激励类型（中性、损失和奖励）的准确性和反应时间进行评估；Stroop 测试中，对每种试验类型（控制和不一致试验）的准确性和反应时间进行评估。从青少年期到成年期，计算 BMI z 分数（∆BMI z 分数）的变化。

结果

BMI z 分数与反眼跳任务准确性之间的关系显示出对 ∆BMI z 分数的影响（β=-0.002，p<0.05）。在超重组（所有β=-0.004，p=0.05）和肥胖组（β=-0.006 和β=-0.005，p<0.01）中，中性和损失的准确性与 ∆BMI z 分数相关。青少年 BMI z 分数与控制（β=-0.312，p<0.001）和不一致（β=-0.384，p<0.001）试验反应时间之间的交互作用对 ∆BMI z 分数有影响。在超重组中，控制（β=0.730，p=0.036）和不一致（β=0.535，p=0.033）试验反应时间与 ∆BMI z 分数相关。