Faculty of Medicine, School of Population and Public Health, University of British Columbia, Vancouver, Canada.
Arthritis Research Canada, Vancouver, BC, Canada.
Rheumatol Int. 2024 Nov;44(11):2279-2292. doi: 10.1007/s00296-024-05575-8. Epub 2024 Mar 26.
We aimed to (1) identify existing triage approaches for referral of patients with suspected inflammatory arthritis (IA) from primary care physicians (PCP) to rheumatologists, (2) describe their characteristics and methodologies for clinical use, and (3) report their level of validation for use in a publicly funded healthcare system. The comprehensive search strategy of multiple databases up to October 2023 identified relevant literature and focussed on approaches applied at the PCP-Rheumatologist referral stage. Primary, quantitative studies, reported in English were included. Triage approaches were grouped into patient conditions as defined by the authors of the reports, including IA, its subtypes and combinations. 13952 records were identified, 425 full text reviewed and 55 reports of 53 unique studies were included. Heterogeneity in disease nomenclature and study sample pretest probability was found. The number of published studies rapidly increased after 2012. Studies were mostly from Europe and North America, in IA and Axial Spondyloarthritis (AxSpa). We found tools ranging the continuum of development with those best performing, indicated by the area under the receiver operating curve (AUC) >0.8), requiring only patient-reported questions. There were AUCs for some tools reported from multiple studies, these were in the outstanding to excellent range for the Early IA Questionnaire (EIAQ) (0.88 to 0.92), acceptable for the Case Finding AxSpa (CaFaSpa) (0.70 to 0.75), and poor to outstanding for the Psoriasis Epidemiology Screening Tool (PEST) (0.61 to 0.91). Given the clinical urgency to improve rheumatology referrals and considering the good.
(1) 识别目前从初级保健医生 (PCP) 将疑似炎症性关节炎 (IA) 患者转诊给风湿病医生的分诊方法;(2) 描述其临床使用的特点和方法;(3) 报告它们在公共资助的医疗保健系统中使用的验证程度。截至 2023 年 10 月,通过对多个数据库的全面搜索策略,确定了相关文献,并重点关注应用于 PCP-风湿病医生转诊阶段的方法。纳入的是报告作者定义的患者病情的主要、定量研究,且报告为英文。分诊方法按报告作者定义的患者病情分组,包括 IA、其亚型和组合。共确定了 13952 条记录,其中 425 条全文进行了回顾,纳入了 55 份报告和 53 项研究。发现疾病命名和研究样本预测试概率存在异质性。2012 年后发表的研究数量迅速增加。研究主要来自欧洲和北美,涉及 IA 和中轴型脊柱关节炎 (AxSpa)。我们发现了一系列开发程度不同的工具,其中表现最好的工具仅需要患者报告的问题,其接收者操作特征曲线 (AUC) 值>0.8)。有些工具的 AUC 值在多个研究中报告,其中早期 IA 问卷 (EIAQ) 的 AUC 值在 0.88 到 0.92 之间,处于优秀到卓越范围;AxSpa 的病例发现 (CaFaSpa) 的 AUC 值在 0.70 到 0.75 之间,处于可接受范围;银屑病流行病学筛查工具 (PEST) 的 AUC 值在 0.61 到 0.91 之间,处于差到优秀范围。鉴于改善风湿病转诊的临床紧迫性,考虑到良好的表现,我们可以认为这些工具具有很大的潜力。