多药耐药菌血流感染和 COVID-19 时代三家希腊三级医院住院患者的医院获得性感染。
Multidrug-resistant organism bloodstream infection and hospital acquisition among inpatients in three tertiary Greek hospitals during the COVID-19 era.
机构信息
Laboratory of Clinical Microbiology, Medical School, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Department of Clinical Microbiology, Tzaneio General Hospital of Piraeus, Athens, Greece.
出版信息
Eur J Clin Microbiol Infect Dis. 2024 Jun;43(6):1241-1246. doi: 10.1007/s10096-024-04806-x. Epub 2024 Mar 26.
From 2019 (pre-COVID-19) to 2022 (COVID-19 years), three tertiary Greek hospitals monitored MDRO bloodstream infection (BSI) and hospital acquisition relying on laboratory data. Surveillance covered carbapenem-resistant Enterobacterales (CRE), Acinetobacter baumannii (CRAB), Pseudomonas aeruginosa (CRPA), vancomycin-resistant enterococci (VRE), and methicillin-resistant Staphylococcus aureus (MRSA), in intensive care units (ICUs) and non-ICUs. Non-ICUs experienced significant increases in CRE, CRAB and VRE during the pandemic. In ICUs, CRE increased in 2021, CRAB in 2020 and 2021, and VRE in 2021 and 2022. KPC predominated among CRE. MDRO BSI and hospital acquisition incidence rates increased, driven by CRE and CRAB.
从 2019 年（新冠疫情前）到 2022 年（新冠疫情年），希腊的三家三级医院依靠实验室数据监测耐多药菌血流感染（BSI）和医院获得性感染。监测范围包括碳青霉烯类耐药肠杆菌科（CRE）、鲍曼不动杆菌（CRAB）、铜绿假单胞菌（CRPA）、万古霉素耐药肠球菌（VRE）和耐甲氧西林金黄色葡萄球菌（MRSA），涉及重症监护病房（ICU）和非 ICU。在疫情期间，非 ICU 中 CRE、CRAB 和 VRE 的数量显著增加。在 ICU 中，2021 年 CRE 增加，2020 年和 2021 年 CRAB 增加，2021 年和 2022 年 VRE 增加。CRE 以 KPC 为主。CRE 和 CRAB 导致 MDRO BSI 和医院获得性感染的发病率增加。
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