Department of Neurorehabilitation, Shengli Oilfield Central Hospital, No. 31 Jinan Road, 257000, Dongying, Shandong, China.
BMC Pulm Med. 2024 Mar 26;24(1):152. doi: 10.1186/s12890-024-02969-z.
The coronavirus disease 2019 (COVID-19) pandemic has resulted in millions of confirmed cases and deaths globally. The purpose of this study was to investigate the therapeutic effect of airway clearance technology combined with prone ventilation on patients infected with COVID-19.
38 patients with COVID-19 (severe) who were treated in the intensive rehabilitation group of Shengli Oilfield Central Hospital. They were randomly divided into a control group and an observation group. The control group received prone position ventilation intervention, and the observation group received airway clearance technology combined with prone position ventilation intervention. The changes of oxygen and index, procalcitonin (PCT), interleukin-6 (IL-6) and chest X-ray image indexes were compared between the two groups.
There was no significant difference in age, gender and other general data between the control group and the observation group. The results showed that oxygen index, PCT, IL-6 and chest X-ray image index in the observation group were better than that indexes in the control group.
Airway clearance technology combined with prone ventilation intervention in patients with COVID-19 can improve the total effective rate and oxygenation index, improve the inflammatory indicators and respiratory function of patients. And it may be widely promoted and used in the treatment of patients with COVID-19 (severe).
2019 年冠状病毒病(COVID-19)大流行已在全球导致数百万人确诊和死亡。本研究旨在探讨气道清除技术联合俯卧位通气对 COVID-19 感染患者的治疗效果。
38 例在胜利油田中心医院重症康复组接受治疗的 COVID-19(重症)患者,随机分为对照组和观察组。对照组接受俯卧位通气干预,观察组接受气道清除技术联合俯卧位通气干预。比较两组患者的氧合指数、降钙素原(PCT)、白细胞介素-6(IL-6)和胸部 X 线影像指标的变化。
对照组和观察组在年龄、性别等一般资料方面无显著差异。结果表明,观察组的氧合指数、PCT、IL-6 和胸部 X 线影像指标均优于对照组。
气道清除技术联合俯卧位通气干预 COVID-19 患者,可提高总有效率和氧合指数,改善患者的炎症指标和呼吸功能,可能在 COVID-19(重症)患者的治疗中得到广泛推广和应用。